Looking ahead, an academic at a public university in Texas, where the money granted for indirect costs funds student salaries, said he plans to hire fewer students for his own lab. “It’s very sad that I cannot promise [positions] at this point because of this,” he told us, adding that the cap could also affect the competitiveness of public universities in Texas, since schools elsewhere may fund their student researchers differently. At the same time, two people with funding through the Defense Department—which could see a surge of investment under the president’s proposed budget—said their projects were moving forward as planned. A biomedical engineer at a public university in the Midwest expressed excitement about what he perceives as a fresh surge of federal interest in industrial and defense applications of synthetic biology. Still, he acknowledged colleagues working on different projects don't feel as optimistic: “Folks are definitely feeling the pressure.” Many who are affected by cuts or delays are now looking for new funding sources in a bid to become less reliant on the federal government. Eleven people said they are pursuing or plan to pursue philanthropic and foundation funding or to seek out industry support. However, the amount of private funding available can’t begin to make up the difference in federal funds lost, and investors often focus more on low-risk, short-term applications than on open scientific questions. The NIH responded to a detailed list of questions with a statement pointing to unspecified investments in early-career researchers. “Recent updates to our priorities and processes are designed to broaden scientific opportunity rather than restrict it, ensuring that taxpayer-funded research is rigorous, reproducible, and relevant to all Americans,” it reads. The NSF declined a request for comment from MIT Technology Review. Further complicating this financial picture are tariffs—some of which are already in effect, and many more of which have been threatened. Nine people who responded to our survey said their work is already being affected by these taxes imposed on goods imported into the US. For some scientists, this has meant higher operating costs for their labs: An AI researcher said tariffs are making computational equipment more expensive, while the Texas academic said the cost of buying microscopes from a German firm had gone up by thousands of dollars since he first budgeted for them. (Neither the White House press office nor the White House Office of Science and Technology Policy responded to requests for comment.) One cleantech entrepreneur saw a positive impact on his business as more US companies reevaluated their supply chains and sought to incorporate more domestic suppliers. The entrepreneur’s firm, which is based in the US, has seen more interest for its services from potential customers seeking “tariff-proof vendors.” “Everybody is proactive on tariffs and we’re one of these solutions—we’re made in America,” he said. Another person, who works for a European firm, is factoring potential tariffs into decisions about where to open new production facilities. Though the Trump administration has said the taxes are meant to reinvigorate US manufacturing, she’s now less inclined to build out a significant presence in the US because, she said, tariffs may drive up the costs of importing raw materials that are required to make the company’s product.