When to watch the San Francisco 49ers vs. LA Rams Thursday, Oct. 2, at 8:15 p.m. ET (5:15 p.m. PT). Where to watch The 49ers and Rams game will stream live on Prime Video and free on Twitch. Fans in the home markets of each team can also watch on a local channel. We have a good one tonight for Thursday Night Football. The 49ers and Rams are tied atop the NFC West at 3-1 with the Seattle Seahawks. The 49ers have been winning despite a rash of injuries to key players. Backup QB Mac Jones will start again in place of Brock Purdy, who will miss another game with a toe injury. The 49ers also will be without its top two receivers in Jauan Jennings and Ricky Pearsall as well as star tight end George Kittle. You can expect Christian McCaffrey to be heavily involved in the 49ers' offense attack tonight. The Rams are the healthier team heading into tonight's game, with Matthew Stafford still playing at a high level in his 17th NFL season and Puka Nacua leading the the league in receptions and receiving yards through the first month of the season. The Niners and Rams kick off tonight at 8:15 p.m. ET (5:15 p.m. PT). The game will stream nationally on Prime Video and free on Twitch. Fans in the San Francisco and Los Angeles markets can watch on a local TV station but the rest of the country will need to stream it on Prime Video or Twitch. Matthew Stafford and the LA Rams host the San Francisco 49ers tonight for Thursday Night Football on Prime Video and Twitch. Brian Rothmuller/Icon Sportswire via Getty Images How to watch 49ers vs. Rams game Tonight's game will stream nationally on Prime Video, giving NFL fans more incentive than free two-day shipping to sign up for an Amazon Prime account, which costs $15 a month or $139 a year. You can also subscribe only to Prime Video for $9 a month. If you don't pay for either of Amazon's services you can watch free on Prime Video's Twitch channel. (Twitch is also owned by Amazon.) You can also use NFL Plus, the league's $7-per-month streaming service (or $15 a month with Red Zone included), to stream the game without subscribing to Prime or Prime Video. Note that NFL Plus viewing is limited to watching on just a phone or tablet, not on a computer or TV. Can I watch the 49ers-Rams game on local TV? Yes, Niners and Rams fans in the local markets of each team will be able to watch the game on an over-the-air station. For this game, that's Fox 2 (KTVU) in San Francisco and Fox 11 (KTTV) in Los Angeles, according to 506 Sports. There are two ways to watch local channels on your TV without cable or satellite TV. The first is with a live TV streaming service. The second is with an over-the-air antenna if you live in an area with good reception. Each of the five major live TV streaming services carry Fox but not every service carries every local network, so check each one using the links below to make sure it carries Fox in your area. All the live TV streaming services above allow you to cancel anytime and require a solid internet connection. Looking for more information? Check out our live TV streaming services guide.