High‑dose Vitamin D reduces disease activity in early multiple sclerosis onset

This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility: Credit: Unsplash/CC0 Public Domain Researchers from CHU Nîmes, Université Montpellier, and multiple MS centers in France have found that oral cholecalciferol in doses of 100,000 IU every two weeks significantly reduced disease activity in clinically isolated syndrome and early relapsing‑remitting multiple sclerosis. The study is published in the journal JAMA. Multiple sclerosis (MS) typically starts with an acute episode involving the central nervous system, such as optic neuritis (inflammation of the optic nerve), transverse myelitis (inflammation of the spinal cord), or brainstem syndromes. This combination of initial signs is termed a clinically isolated syndrome (CIS), although CIS does not always convert to MS. The risk factors for relapse (conversion to clinically definite MS) include the presence ... Read full article.