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Roc-based DEFLATE package closes performance gap with C's libdeflate

A developer spent time optimizing roc-deflate, a DEFLATE compression package for the Roc functional programming language written by Niclas Ahden, aiming to see how close it could get to the performance of libdeflate, the C library widely regarded as the fastest DEFLATE implementation. The effort followed an earlier result showing a Lean 4 library, lean-zip, beating Rust's popular miniz_oxide package but still falling well short of libdeflate, which uses hand-tuned, architecture-specific SIMD code. Testing used the non-streaming APIs and the Silesia corpus, since roc-deflate does not yet support streaming.

University of Kentucky study restores mice sleep by targeting immune cells, not plaques

Researchers at the University of Kentucky found that temporarily depleting microglia, the brain's resident immune cells, restored more than two hours of sleep per day in mice with Alzheimer's-like brain changes, without removing amyloid plaques. The team, led by Shannon L. Macauley and first author Nicholas J. Constantino, published the findings in Alzheimer's & Dementia, showing mice also spent more time in deep, restorative sleep stages.

rqlite creator marks 12 years of Raft-replicated SQLite project

The developer behind rqlite, an open-source system that pairs SQLite with the Raft consensus protocol, published a retrospective marking the project's origin in September 2014. He recounts building it to solve a storage problem at jut.io, switching its Raft implementation from goraft to Hashicorp's Raft in 2016, and designing it as a CP system where writes require majority acknowledgment through a leader node.

Ethereum delays Glamsterdam upgrade on Hoodi testnet, pausing 200M gas-limit test

Ethereum core developers postponed the Glamsterdam upgrade activation on the Hoodi testnet, originally set for October 26, following discussion at ACDE #248 on October 22. The delay, announced via the Ethereum Foundation blog, cancels the Amsterdam and Gloas activations and the planned increase of Hoodi's gas limit to roughly 200M, citing a need to study EIP-8037's interaction with deployed smart contracts.

UK commits £100m to new national AI Biosecurity Lab

The UK government announced it will fund a national AI Biosecurity Lab (AIBL) with £100m in Wednesday's Budget, describing it as a 'world first' institute to counter biological and AI-enabled threats. OpenAI and Anthropic will support the effort with £200m worth of AI model credits, though specific details about the lab's structure and remit have not yet been released.

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