The Download: a “dire wolf” revival, and safeguarding AI companions

For several years now, Texas-based company Colossal Biosciences has been in the news for its plans to re-create woolly mammoths someday. But now it’s making a bold new claim—that it has actually “de-extincted” an animal called the dire wolf. Dire wolves were large, big-jawed members of the canine family. More than 400 of their skulls have been recovered from the La Brea Tar Pits in California. Ultimately they were replaced by smaller relatives like the gray wolf. In its effort to re-create the animal, Colossal says, it extracted DNA information from dire wolf bones and used gene editing to introduce some of those elements into cells from gray wolves. It then used a cloning procedure to turn the cells into three actual animals. But some scientists reject the company’s claim that the new animals are a revival of the extinct creatures, since in reality dire wolves and gray wolves are different species separated by a few million of years of evolution and several million letters of DNA ... Read full article.