The FDA Warns of New Zyrtec and Xyzal Side Effect. What Is Pruritus?
Published on: 2025-06-13 07:20:02
According to the FDA, 62.7 million over-the-counter packages of Zyrtec (cetirizine) and Xyzal (levocetirizine) were purchased in 2022. Since allergies are getting worse -- partly because of climate change creating longer, more intense pollen seasons -- these numbers have likely climbed in the last three years as more people purchase the antihistamines to cope with allergy symptoms like a stuffy nose, watery, red, itchy eyes and hives.
For the millions of people who take these drugs, it's important to know that the FDA recently published a warning about a newly discovered side effect that may occur after taking both Zyrtec and Xyzal.
If you stop taking Zyrtec or Xyzal after long-term use, you might experience "rare but severe" itching. Also called pruritus, this itching was experienced by patients who had been taking these allergy medicines every day for several months or years and then stopped.
What is the FDA going to do?
The FDA decided to issue this warning after identifying 209
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