Earlier this year, Monadic DNA kicked off an experiment to demonstrate that people can access and analyze their genetic data with anonymity and privacy.
Monadic DNA collected saliva samples from thirty encrypted genomics pioneers at an event in Denver. These participants later used a Web app to claim their genotyping results using a unique kit ID and a self-selected PIN.
The app guided users through uploading their data to encrypted storage powered by Nillion’s multi-party compute (MPC) technology. From there, users could generate insights without exposing their raw genomic data. Computations were performed on the server-side using MPC without decryption and then processed and revealed locally.
This experiment offers a practical model for handling sensitive genetic information in a way that prioritizes privacy, security, and data sovereignty.
Sample Collection
The sample collection event happened in late February during the ethDenver conference. We chose Terminal Bar at Union Station for its central location and copious outdoor seating during some excellent weather. A Luma event during a busy conference and some social media posts were enough to draw a decent crowd.
We underestimated the turnout so we didn’t end up having enough sample collectors. It was good to have our own designated area so we wouldn’t unduly worry anyone with our medical equipment. 🙂
The lucky thirty that made it on time were given a standard sample collector and asked to spit into it until they hit a marked level. We provided latex gloves to everyone involved and all refuse was collected in a bag for proper disposal. Before providing a sample, each participant had to fill in a form agreeing to some legalese and record their kit ID and pick a four-digit PIN for the later data claim. They also had the option to provide an email address, Signal ID or Telegram ID in case they wanted to receive updates. Participants couldn’t eat or drink for thirty minutes before providing a sample but, for humane reasons, were provided with a beverage of their choice right after they were done with their sample collectors.
Those who wished could also claim a POAP to mark their participation in this event. Surprisingly, most participants were highly interested in the POAP and others went to decent lengths to get their POAP afterwards once they realized they had missed the bit about getting a virtual collectible.
Regular people walking by couldn’t help being interested in the event after seeing the equipment and general fanfare. Unfortunately, we had not accounted for this in advance and didn’t budget enough collectors to include walk-ins. It was good to have a team of three organizing the event as things would have become chaotic otherwise.
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