Researchers are redesigning drug molecules and delivery systems so a single injection or implant can maintain therapeutic effects for weeks, months, or even years instead of requiring daily dosing. Techniques include chemical modifications that slow drug breakdown, polymer depots, and implantable devices that release medication gradually over extended periods.
Across decades of reboots, films and animated series, Peter Cullen has consistently returned as the voice of Optimus Prime, providing continuity to the Transformers franchise regardless of who else is involved in a given production. His presence has become a defining thread linking the many different creative visions the property has cycled through.
Peter Cullen, the Canadian voice actor who gave life to Optimus Prime across Transformers films, TV shows and games, has died at his Los Angeles home. He was also known for voicing Eeyore in Winnie the Pooh productions, King Kong in the 1976 remake, and the villainous K.A.R.R. on Knight Rider. His family confirmed he passed peacefully, surrounded by loved ones.