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Study maps mutation patterns across Arabidopsis centromeres using multi-generation lines

Researchers analyzed four Arabidopsis thaliana datasets—MA16 and MA32 mutation-accumulation lines, HPG1 natural accessions, and rtel1-1 repair mutants—to track how centromeric DNA changes over generations. High-molecular-weight DNA was extracted and sequenced using PacBio HiFi and Illumina platforms at facilities including the Max Planck Genome Centre and Max Planck Institute for Biology Tübingen.

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