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Gene Therapy Slows Huntington’s by 75% in ‘Groundbreaking’ Clinical Trial

gizmodo.com Ed Cara 2025-09-25 21:15:06

Doctors in the UK are claiming to have performed a monumental medical breakthrough. Using a form of gene therapy, they successfully treated—for the first time—the neurodegenerative disorder Huntington’s disease. On Wednesday, the company uniQure announced the results of its phase I/II trial testing the therapy, code-named AMT-130. The trial, conducted with the help of researchers from University College London, found that AMT-130 slowed the progression of people’s symptoms by 75%. It also appea

Topics: brain disease huntington people therapy
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In Major Breakthrough, Scientists Successfully Treat Devastating Brain Disease Huntington’s for the First Time

futurism.com Victor Tangermann 2025-09-26 17:15:56

A research team says that for the first time in history, it’s successfully treated Huntington’s disease, a devastating and inherited disorder that kills nerve cells and leads to rapid decline and death. Until now, the disease had no treatment to cure it or alter its course. Patients tend to succumb to the disease within 15 to 20 years after the onset of symptoms, which include trouble focusing, irritability, suicidal thoughts, and other mental health conditions, as well as uncontrolled movement

Topics: disease gene huntington percent therapy
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Huntington's disease treated for first time

news.ycombinator.com Unknown 2025-09-27 14:37:30

Huntington's disease successfully treated for first time 55 minutes ago Share Save James Gallagher Health and science correspondent Share Save BBC/Fergus Walsh Professors Ed Wild and Sarah Tabrizi led the UK part of the trial One of the cruellest and most devastating diseases – Huntington's – has been successfully treated for the first time, say doctors. The disease runs through families, relentlessly kills brain cells and resembles a combination of dementia, Parkinson's and motor neurone dis

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The King's Quarry: How Louis XVI Went from Hunter to Hunted

news.ycombinator.com George Dillard 2025-11-06 09:52:47

Marie Antoinette on the hunt ( Public domain ) One of the most famous diary entries of all time consists of a single word: rien, which is French for “nothing.” It’s what King Louis XVI recorded on July 14, 1789, the day the Bastille was stormed. This entry (or lack thereof) is often cited as evidence of the king’s disinterest in the brewing revolution. The standard narrative about Louis is that he was simply not up to the task of dealing with the forces that threatened his throne. As a second

Topics: hunt hunting king louis royal
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Orcas Pretend to Drown Each Other in Rare Training Session Caught on Camera

gizmodo.com Margherita Bassi 2025-12-25 22:10:22

Orcas are called “killer whales” (even though they’re technically dolphins) for good reason. They’re the ocean’s top predators, hunting down everything from great white sharks to blue whales—the largest animal in the world. But orcas aren’t born killers. It’s a skill they learn from their elders and, as new evidence suggests, practice on each other. Parenthood, a new five-part BBC wildlife series narrated by David Attenborough, includes the first known footage of orcas learning how to drown the

Topics: bbc got hunting orcas practice
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E.A. Spitzka's Studies of Exceptional and Deviant Brains (2024)

news.ycombinator.com Unknown 2026-03-08 13:11:30

The younger Spitzka’s career flourished after he took a position at Thomas Jefferson University in Philadelphia, where he gained recognition for his studies on the relationship between brain structures and behavior. His particular interest lay in the extremes of human nature—both pathological and extraordinary—and he sought to understand the physiology behind deviance and brilliance. In addition to his academic pursuits, Spitzka served as the editor of the 1910 edition of Gray’s Anatomy, one of

Topics: american brain collection huntington spitzka
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