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WIRED Health Recap: Cancer Vaccines, Crispr Breakthroughs, and More

wired.com Wired Staff 2025-09-26 20:30:00

At the WIRED Health summit in Boston on September 9, we hosted some of the leading experts in Crispr, whole-genome sequencing, vaccines, and more for a series of eye-opening conversations and keynotes. If you weren’t able to join us in person, no worries; you can watch them all right here. From 2025 Breakthrough Prize winner David Liu to Moderna CEO Stepháne Bancel, WIRED Health speakers gave deep insights into what’s next for gene-editing, cancer treatment, and a host of other cutting-edge top

Topics: cancer diseases health new wired

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The Next Era of Gene Editing Will Be Disease Agnostic

wired.com Emily Mullin 2025-09-28 07:30:00

At the WIRED Health summit last week, Harvard biochemist and gene-editing pioneer David Liu says later this year his lab plans to report on a single gene-editing strategy that could treat many unrelated diseases. He calls it disease-agnostic therapeutic gene editing. “It sounds sort of crazy, but there’s actually a very good molecular biology reason why this could be possible,” he told the audience in Boston, stopping short of details. Gene-editing treatments are currently being developed for

Topics: disease diseases editing gene genetic

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WIRED Health Recap: Cancer Vaccines, CRISPR Breakthroughs, and More

wired.com Wired Staff 2025-09-28 07:30:00

At the WIRED Health summit in Boston on September 9, we hosted some of the leading experts in CRISPR, whole-genome sequencing, vaccines, and more for a series of eye-opening conversations and keynotes. If you weren’t able to join us in person, no worries; you can watch them all right here. From 2025 Breakthrough Prize winner David Liu to Moderna CEO Stepháne Bancel, WIRED Health speakers gave deep insights into what’s next for gene-editing, cancer treatment, and a host of other cutting-edge top

Topics: cancer diseases health new wired

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Whole-Genome Sequencing Will Change Pregnancy

wired.com Rob Reddick 2025-09-28 09:00:00

The world of pregnancy is going to radically change, predicts Noor Siddiqui. “I think that the default way people are going to choose to have kids is via IVF and embryo screening,” she said at the WIRED Health summit last week. “There’s just a massive amount of risk that you can take off of the table.” Siddiqui is the founder and CEO of Orchid, a biotech company that offers whole-genome screening of embryos for IVF. By analyzing the DNA of different embryos before selecting which one to implant

Topics: disease embryos genetic risk siddiqui

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New Bacteria Discovered in Flies Could Sicken Humans

gizmodo.com Margherita Bassi 2025-10-06 20:35:14

A new species of bacteria has come to light in Brazil. It’s genetically similar to two other disease-causing bacteria from the Andes, which are known to infect humans through sand fly bites. According to a study published this summer in the journal Acta Tropica, researchers have discovered a new bacteria species in phlebotomine insects (sand flies) in the Amazon National Park in Brazil’s state of Pará. Its DNA is similar to that of two Andean bacteria in Peru, Bartonella bacilliformis and Barto

Topics: bacteria bartonella disease sand species

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RFK Jr’s plan to improve America’s diet is missing the point

technologyreview.com Jessica Hamzelou 2025-10-22 13:00:00

“I’m working with Linda on forcing medical schools … to put nutrition into medical school education,” Kennedy said during a cabinet meeting on August 26. The next day, HHS released a statement calling for “increased nutrition education” for medical students. “We can reverse the chronic-disease epidemic simply by changing our diets and lifestyles,” Kennedy said in an accompanying video statement. “But to do that, we need nutrition to be a basic part of every doctor’s training.” It certainly sou

Topics: disease education medical nutrition said

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Climate Change Is Bringing Legionnaire’s Disease to a Town Near You

wired.com Dylan Scott 2025-10-31 15:00:00

This story originally appeared on Vox and is part of the Climate Desk collaboration. Air conditioners have been working overtime this hot summer, from those tiny window units to the massive AC towers that serve the tightly packed apartment buildings in major cities. And while they bring the relief of cool air, these contraptions also create the conditions for dangerous bacteria to multiply and spread. One particularly nasty bacteria-borne illness is currently spreading in New York City using t

Topics: air bacteria city disease legionnaire

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Plague Case Confirmed Near Lake Tahoe After Likely Flea Bite

gizmodo.com Natalia Mesa 2025-11-07 03:55:17

A California resident has tested positive for the plague after camping near Lake Tahoe, local health officials confirmed. It’s the latest in a string of positive cases in the western U.S. this year. The infected person was likely bitten by a plague-infected flea in the South Lake Tahoe area, according to local health officials. This is the first local case in the area since 2020. The person is currently recovering and is undergoing medical treatment at home. “Plague is naturally present in man

Topics: according california disease health plague

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Possible Local Malaria Case Found in New Jersey. Here’s What to Know

gizmodo.com Ed Cara 2025-11-10 17:10:15

A once-vanquished disease spread by mosquitoes may be making inroads into the United States. New Jersey officials are now investigating whether a resident’s malaria infection was locally acquired. The New Jersey Departments of Health (NJDOH) and Environmental Protection reported on the case Monday. The resident hadn’t recently traveled, suggesting they likely caught it from homegrown mosquitoes. If so, this would be the first locally acquired malaria case seen in the state in over three decades

Topics: case disease malaria mosquito mosquitoes

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Vitamin E: Health Benefits, Food Sources and What to Know Before Using Supplements

cnet.com See Full Bio 2025-11-27 08:32:00

You may have noticed vitamin E on the label of your favorite skin-care products. It's a nutrient that can help protect your skin from UV damage, making it a common ingredient for facial sunscreens. But vitamin E isn't just applied topically -- you also need to get it in your daily diet. Consuming enough vitamin E is crucial because it plays a key role in human development and functioning. The vitamin includes eight compounds, but only one of those -- alpha-tocopherol -- is used in the human body

Topics: daily disease like risk vitamin

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Travelers Are Unknowingly Smuggling Invasive Ticks Into the U.S.

gizmodo.com Ed Cara 2025-11-29 02:30:32

Here’s an important tip for international travelers coming back home: Be sure to check for any blood-sucking creepy-crawlies attached to you. In a study out today, health experts warn that exotic, potentially disease-carrying ticks are regularly entering the U.S. by hitching a ride onto returning Americans. Tick scientists in Connecticut conducted the research, published Friday in the journal iScience. They detailed seven separate cases of nonnative ticks entering the state via travelers in rec

Topics: diseases molaei nonnative tick ticks

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Woman Diagnosed with Malaria in Washington May Be State’s First Locally Acquired Case

gizmodo.com Natalia Mesa 2025-12-01 06:55:11

Washington state officials have revealed that a local woman has been diagnosed with malaria, which, if confirmed, would mark the first known case of the disease being acquired in the state. The woman was diagnosed with malaria, a mosquito-borne illness caused by a parasite, on August 2, according to the officials. State and federal public health agencies are working to confirm the source of the infection, according to a statement published on Wednesday. Officials believe that the infection may

Topics: according cases disease infected malaria

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Lithium compound can reverse Alzheimer’s in mice: study

news.ycombinator.com Stephanie Dutchen 2025-12-01 12:56:05

“The idea that lithium deficiency could be a cause of Alzheimer’s disease is new and suggests a different therapeutic approach,” said senior author Bruce Yankner, professor of genetics and neurology in the Blavatnik Institute at HMS, who in the 1990s was the first to demonstrate that amyloid beta is toxic. The study raises hopes that researchers could one day use lithium to treat the disease in its entirety rather than focusing on a single facet such as amyloid beta or tau, he said. One of the

Topics: alzheimer brain disease lithium yankner

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Lithium Reverses Alzheimer's in Mice

news.ycombinator.com Stephanie Dutchen 2025-12-01 18:56:05

“The idea that lithium deficiency could be a cause of Alzheimer’s disease is new and suggests a different therapeutic approach,” said senior author Bruce Yankner, professor of genetics and neurology in the Blavatnik Institute at HMS, who in the 1990s was the first to demonstrate that amyloid beta is toxic. The study raises hopes that researchers could one day use lithium to treat the disease in its entirety rather than focusing on a single facet such as amyloid beta or tau, he said. One of the

Topics: alzheimer brain disease lithium yankner

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NYC Legionnaires’ Disease Outbreak: Cases and Deaths Double, as Officials Pinpoint the Cause

gizmodo.com Ed Cara 2025-12-07 11:10:42

An outbreak of Legionnaires’ disease in NYC has doubled in reported cases and deaths since last week. Officials have struggled to identify the source of the outbreak, but it has now been confirmed. Officials at the NYC Health Department issued the latest update on the outbreak Monday. Fifty-eight people living in Central Harlem have been diagnosed with Legionnaires’ since July 25, while two people have died from it. On the positive side, officials have identified several cooling towers contamin

Topics: bacteria disease health legionnaires officials

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How Not to Study a Disease (2023)

news.ycombinator.com Written By 2025-12-15 11:03:16

Image credit: @ionut.stefan.92ish Română In today’s post, I’d like to draw your attention to an absolutely amazing book on the topic of Alzheimer’s disease. Written by Prof. Karl Herrup, professor of neurobiology at the University of Pittsburgh School of Medicine, “How Not to Study a Disease – The Story of Alzheimer’s” takes the reader on a journey of Alzheimer’s research from its inception by Alois Alzheimer to the contemporary understanding of this devastating condition. This is not just an

Topics: alzheimer amyloid disease herrup research

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A Deadly Outbreak of Legionnaires’ Disease Is Hitting NYC

gizmodo.com Ed Cara 2025-12-15 11:05:01

A deadly outbreak of Legionnaires’ disease is ripping through Central Harlem in New York City. Local health officials report that about two dozen residents have been sickened by the pneumonia-causing bacteria so far this month. The NYC Health Department issued its latest update on the outbreak Wednesday, following its first report last week. Since July 25, there have been 22 cases of Legionnaires’ disease diagnosed throughout the area, along with one death. Residents in the affected neighborhoo

Topics: bacteria disease health legionnaires symptoms

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What Your Nighttime Breathing Says About Your Health

wired.com Anna Mckie 2025-12-19 12:00:00

For decades, sleep disturbance was a punch line: the cartoon dad snoring, the disgruntled partner burying their head under a pillow. But science is beginning to paint a less jovial picture. Sleep apnea—a relatively common disorder where breathing repeatedly stops and starts during sleep—is now being taken seriously as a potential biomarker for a host of major health conditions, from cardiovascular disease to Alzheimer’s, even anxiety and depression. “Sleep is just as important for health as die

Topics: apnea brain disease says sleep

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There's Neuralink—and There's the Mind-Reading Company That Might Surpass It

wired.com Emily Mullin 2026-01-07 16:00:00

Mark Jackson is playing a computer game with his mind. As he reclines in bed, three blue circles appear on a laptop screen a few feet away. One turns red: the target. Jackson is in control of a white circle, which he needs to steer into the target without running into the blue obstacles. The game is a bit like Pac-Man. Except instead of a joystick, Jackson uses his thoughts to control his little white circle. To move left, he thinks about clenching his right fist once. To move right, he thinks a

Topics: als brain disease game jackson

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Babies made using three people's DNA are born free of mitochondrial disease

news.ycombinator.com Unknown 2026-01-03 23:43:35

Babies made using three people's DNA are born free of hereditary disease 3 days ago Share Save James Gallagher • @JamesTGallagher Health and science correspondent Share Save Watch the moment DNA from a mum and dad is injected into the egg of another woman - the critical step in the creation of a baby made from three people Eight babies have been born in the UK using genetic material from three people to prevent devastating and often fatal conditions, doctors say. The method, pioneered by UK s

Topics: babies born disease mitochondria mitochondrial

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3D-printed living lung tissue

news.ycombinator.com Patty Wellborn 2026-01-10 11:20:42

UBC Okanagan researchers have developed a 3D bio-printed model that closely mimics the complexity of natural lung tissue, an innovation that could transform how scientists study lung disease and develop new treatments. Dr. Emmanuel Osei, Assistant Professor in the Irving K. Barber Faculty of Science, says the model produces tissue that closely resembles the complexity of a human lung, enabling improved testing of respiratory diseases and drug development. “To conduct our research and the testi

Topics: disease lung model osei tissue

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Hot Tick Summer Is Here. Here’s What You Need to Know and How to Stay Safe

gizmodo.com Ed Cara 2026-01-20 21:00:28

Summer in the U.S. is now in full swing. That means plenty of outdoor fun, Sun, and, unfortunately, for many of us, tiny eight-legged ticks to avoid. Ticks and the many illnesses they carry, like Lyme disease, are a growing public health threat. Just this week, for instance, the latest data from the Centers for Disease Control and Prevention showed that 2025 so far has seen the highest number of tick-related emergency room visits recorded since 2019. And though the worst tick species are especi

Topics: disease diseases tick tickborne ticks

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Large-scale DNA study maps 37,000 years of human disease history

news.ycombinator.com Unknown 2026-01-25 08:42:58

A new study suggests that our ancestors’ close cohabitation with domesticated animals and large-scale migrations played a key role in the spread of infectious diseases. The team, led by Professor Eske Willerslev at the Universities of Cambridge and Copenhagen, recovered ancient DNA from 214 known human pathogens in prehistoric humans from Eurasia. They found that the earliest evidence of zoonotic diseases – illnesses transmitted from animals to humans, like COVID in recent times – dates back t

Topics: ago diseases dna humans years

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So you wanna build an aging company

news.ycombinator.com Sarah Constantin 2026-01-30 11:30:30

Today, aging is cool. In 2024 alone, investors deployed about $8.5B into longevity-focused biotech companies. Aging biotech companies have entered clinical trials. The field has come a long way. But as “aging” (and “longevity”) have become more mainstream, there’s a temptation to stretch the definition to things that don’t belong in the category. Aging is not a single process. It’s a complex interplay of multiple biological processes that, over time, become dysregulated. Understanding it as suc

Topics: age aging disease like related

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We’re learning more about what weight-loss drugs do to the body

technologyreview.com Jessica Hamzelou 2026-02-19 20:00:00

We know they can suppress appetite, lower blood sugar, and lead to dramatic weight loss. We also know that they come with side effects, which can include nausea, diarrhea, and vomiting. But we are still learning about some of their other effects. On the one hand, these seemingly miraculous drugs appear to improve health in other ways, helping to protect against heart failure, kidney disease, and potentially even substance-use disorders, neurodegenerative diseases, and cancer. But on the other,

Topics: disease effects glp people weight

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Tick Bite? Here's What to Know About Lyme Disease and Your Next Steps

cnet.com See Full Bio 2026-02-23 20:00:05

You just finished a satisfying summer hike or wrapped up a weekend of yard work when you spot a tick clinging to your clothes. The fresh-air high fades quickly as you remember the risks -- ticks are known carriers of Lyme disease, a growing concern across the US. Lyme disease cases have more than doubled in recent years, according to the CDC, with annual reports jumping from around 42,000 to nearly 90,000. While part of that increase is due to improved detection and reporting methods, the risk

Topics: disease harker lyme symptoms tick

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The United States has lower life expectancy than most similarly wealthy nations

news.ycombinator.com Pearson 2026-02-27 05:30:50

Since taking over as the top US health official in February, Robert F. Kennedy Jr has overseen radical changes that have alarmed many public-health experts. The agency he leads announced that it would cut its workforce by 20,000, and cancelled billions of dollars in federal funding for research and public health. Earlier this month, Kennedy replaced all the members of an influential vaccine advisory committee with hand-picked ones, including some who have expressed scepticism about vaccines. His

Topics: disease health says states united

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After RFK Jr. overhauls CDC panel, measles and flu vaccines are up for debate

arstechnica.com Unknown 2026-03-08 23:42:46

With ardent anti-vaccine activist Robert F. Kennedy Jr. in the country's top health position, use of a long-approved vaccine against measles, mumps, rubella, and varicella/chickenpox (MMRV) as well as flu shots that include the preservative thimerosal will now be reevaluated, putting their future availability and use in question. The development seemingly continues to vindicate health experts' worst fears that, as health secretary, Kennedy would attack and dismantle the federal government's scie

Topics: acip disease rsv vaccine vaccines

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Latest Tech News

WIRED Health Recap: Cancer Vaccines, Crispr Breakthroughs, and More

The Next Era of Gene Editing Will Be Disease Agnostic

WIRED Health Recap: Cancer Vaccines, CRISPR Breakthroughs, and More

Whole-Genome Sequencing Will Change Pregnancy

New Bacteria Discovered in Flies Could Sicken Humans

RFK Jr’s plan to improve America’s diet is missing the point

Climate Change Is Bringing Legionnaire’s Disease to a Town Near You

Plague Case Confirmed Near Lake Tahoe After Likely Flea Bite

Possible Local Malaria Case Found in New Jersey. Here’s What to Know

Vitamin E: Health Benefits, Food Sources and What to Know Before Using Supplements

Travelers Are Unknowingly Smuggling Invasive Ticks Into the U.S.

Woman Diagnosed with Malaria in Washington May Be State’s First Locally Acquired Case

Lithium compound can reverse Alzheimer’s in mice: study

Lithium Reverses Alzheimer's in Mice

NYC Legionnaires’ Disease Outbreak: Cases and Deaths Double, as Officials Pinpoint the Cause

How Not to Study a Disease (2023)

A Deadly Outbreak of Legionnaires’ Disease Is Hitting NYC

What Your Nighttime Breathing Says About Your Health

There's Neuralink—and There's the Mind-Reading Company That Might Surpass It

Babies made using three people's DNA are born free of mitochondrial disease

3D-printed living lung tissue

Hot Tick Summer Is Here. Here’s What You Need to Know and How to Stay Safe

Large-scale DNA study maps 37,000 years of human disease history

So you wanna build an aging company

We’re learning more about what weight-loss drugs do to the body

Tick Bite? Here's What to Know About Lyme Disease and Your Next Steps

The United States has lower life expectancy than most similarly wealthy nations

After RFK Jr. overhauls CDC panel, measles and flu vaccines are up for debate

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