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GLP-1s are breaking life insurance

news.ycombinator.com Ashwin Sharma 2025-07-28 08:31:47

GPT/GLP-1 Illustration Hello and happy Sunday! Was this newsletter forwarded to you? Sign up to get it in your inbox. I've just got back from HLTH in Amsterdam, nursing what might be the worst three-day hangover of my adult life. Worth it, though. It's one of the best health tech events in Europe, and I made some genuinely great connections. If you’re ever at a large health conference, here’s a neat little hack I learned: Be brave enough to ask questions during panels. It's terrifying, but su

Topics: glp health insurers weight year

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GLP-1s Are Breaking Life Insurance

news.ycombinator.com Ashwin Sharma 2025-07-28 23:31:47

GPT/GLP-1 Illustration Hello and happy Sunday! Was this newsletter forwarded to you? Sign up to get it in your inbox. I've just got back from HLTH in Amsterdam, nursing what might be the worst three-day hangover of my adult life. Worth it, though. It's one of the best health tech events in Europe, and I made some genuinely great connections. If you’re ever at a large health conference, here’s a neat little hack I learned: Be brave enough to ask questions during panels. It's terrifying, but su

Topics: glp health insurers weight year

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Scientists Gene Hack Mice So Their Livers Produce Their Own Ozempic-Like Drug

futurism.com Unknown 2025-07-29 05:51:22

Image by Remi Benali/Getty Images Rx/Medicines Scientists have gene-hacked mice to produce their own Ozempic-like drugs — possibly, and provocatively, perhaps paving a path for humans to do so themselves one day. In a new study published in the journal Communications Medicine, researchers from Japan's University of Osaka successfully gene-edited mice livers to produce exenatide, a first-generation diabetes drug and predecessor to now-trendy jabs like Ozempic and Mounjaro. Using lab mice that

Topics: gene glp mice ozempic researchers

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These Genetically Modified Mice Make Their Own ‘Ozempic’

gizmodo.com Ed Cara 2025-08-03 22:05:53

The popularity of Ozempic and Wegovy as diabetes and weight loss medications has skyrocketed. But how far would people go to avoid one of their major drawbacks—the need for weekly injections? A study out today shows it’s possible to genetically modify mice to make their own Ozempic-like drugs. Scientists in Japan led the research, which involved gene-editing mice’s livers to produce an internal supply of exenatide, a first-generation GLP-1 drug. The edited mice were able to sustain levels of th

Topics: drugs gene glp mice people

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Could Ozempic Treat Migraines, Too? Small Study Finds Early Promise for GLP-1s

gizmodo.com Ed Cara 2025-08-20 02:25:30

Got a blinding headache? Some GLP-1 therapy could surprisingly help. A recent clinical trial has found early evidence that these popular drugs, typically used to treat obesity and type 2 diabetes, may also reduce migraine episodes. Researchers in Italy conducted the small pilot trial, which involved dozens of patients living with obesity and chronic migraine headaches. People experienced a significant drop in the number of migraine days each month upon taking liraglutide, the researchers found—

Topics: 1s drug glp migraine migraines

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We’re learning more about what weight-loss drugs do to the body

technologyreview.com Jessica Hamzelou 2025-08-23 01:00:00

We know they can suppress appetite, lower blood sugar, and lead to dramatic weight loss. We also know that they come with side effects, which can include nausea, diarrhea, and vomiting. But we are still learning about some of their other effects. On the one hand, these seemingly miraculous drugs appear to improve health in other ways, helping to protect against heart failure, kidney disease, and potentially even substance-use disorders, neurodegenerative diseases, and cancer. But on the other,

Topics: disease effects glp people weight

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Spike in Pancreas Problems From Weight-Loss Drugs Prompts Investigation

gizmodo.com Ed Cara 2025-08-24 14:37:46

Ozempic and similar GLP-1 drugs seem to be hurting some people’s pancreas. UK health officials are planning to study the link between GLP-1 use and acute pancreatitis, following an increase in reported cases this year. The Guardian reported Tuesday that the UK’s Medicines and Healthcare Products Regulatory Agency (MHRA) is launching an investigation into pancreatitis associated with the drug class. Hundreds of residents have complained about pancreas problems after taking semaglutide or other r

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Ozempic Might Be a Dementia Buster, Too

gizmodo.com Ed Cara 2025-08-29 00:55:27

Semaglutide, the active ingredient in popular weight loss drugs Ozempic and Wegovy, might also double as a brain booster. Research out today describes a link between semaglutide use and a reduced risk of dementia in people with type 2 diabetes. Scientists at Case Western Reserve University conducted the study, published in the Journal of Alzheimer’s Disease. They found that diabetes patients taking semaglutide have a significantly lower risk of dementia than those taking other diabetes medicati

Topics: dementia diabetes glp risk semaglutide

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Novo Nordisk Abruptly Ends Partnership with Hims, Claiming ‘Sham Compounding’ GLP-1 Drugs

gizmodo.com Ed Cara 2025-08-30 22:04:21

Bad blood is brewing among some major players in the weight loss world. Novo Nordisk, the creator of Ozempic and Wegovy, cut short its partnership with telehealth company Hims & Hers Health Inc. over allegations that the latter is still trying to mass-market cheaper versions of the GLP-1 drugs. Bloomberg News reported the abrupt dissolution of the partnership Monday, just two months after it was struck. Novo claims that Hims is using “deceptive marketing” to widely sell compounded semaglutide t

Topics: compounded drugs glp hims novo

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Eli Lilly’s Obesity Pill Appears to Work as Well as Injected GLP-1s

wired.com Emily Mullin 2025-09-01 00:01:00

Eli Lilly’s daily anti-obesity pill orforglipron appears to be as good at spurring weight loss and lowering blood sugar in diabetes patients as popular injectable GLP-1 drugs like Ozempic, according to new data from a Phase 3 trial. The results were announced today at the annual meeting of the American Diabetes Association and published in the New England Journal of Medicine. Eli Lilly is the maker of the blockbuster GLP-1 drug tirzepatide, approved as Mounjaro for type 2 diabetes and Zepbound

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Surgery Still Beats Ozempic and Other GLP-1 Drugs in Real-World Weight Loss Study

gizmodo.com Ed Cara 2025-09-09 06:05:43

When it comes to weight loss, surgery still reigns supreme. Research out today shows that people undergoing bariatric surgery tend to lose significantly more weight than people taking the newest, most effective GLP-1 medications for obesity. Scientists at New York University conducted the study, which analyzed real-world data from obesity patients. People who received surgery lost five times more weight over a two year span on average than those who were prescribed a GLP-1 drug, they found. The

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Doctors Concerned By Massive Uptick In Teens Taking Ozempic

futurism.com Unknown 2025-09-15 23:15:15

Image by Roberto Pfeil / picture alliance via Getty / Futurism Rx/Medicines Teens are being prescribed Ozempic and similar drugs more than ever before — and some doctors are worried about what the trend could mean. In interviews with Reuters and Raleigh, North Carolina's WRAL, doctors expressed disquiet at recent studies that found that are kids being prescribed the uber-popular jabs at increasing rates. Two recent studies, the first from the from the data firm Truveta and the second from Eve

Topics: doctors drugs glp kids ozempic

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Latest Tech News

GLP-1s are breaking life insurance

GLP-1s Are Breaking Life Insurance

Scientists Gene Hack Mice So Their Livers Produce Their Own Ozempic-Like Drug

These Genetically Modified Mice Make Their Own ‘Ozempic’

Could Ozempic Treat Migraines, Too? Small Study Finds Early Promise for GLP-1s

We’re learning more about what weight-loss drugs do to the body

Spike in Pancreas Problems From Weight-Loss Drugs Prompts Investigation

Ozempic Might Be a Dementia Buster, Too

Novo Nordisk Abruptly Ends Partnership with Hims, Claiming ‘Sham Compounding’ GLP-1 Drugs

Eli Lilly’s Obesity Pill Appears to Work as Well as Injected GLP-1s

Surgery Still Beats Ozempic and Other GLP-1 Drugs in Real-World Weight Loss Study

Doctors Concerned By Massive Uptick In Teens Taking Ozempic

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