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Ozempic May Be Less Effective for Emotional Eaters, Study Suggests

GLP-1 agonists—so-called “wonder drugs” like Ozempic or Wegovy that help individuals lower blood sugar levels and lose weight, among other things—yield significant results for some patients, but not all. People’s motivations to overeat may play a role in this, according to a new study. To investigate why some people don’t benefit from GLP-1 agonists as much as others, researchers observed 92 participants with type 2 diabetes in Japan during their first year of taking GLP-1 drugs. Their results,

Ozempic Is an ‘Essential’ Drug, WHO Says as Agency Calls for Cheaper Generics

One of the world’s most sought-after drugs has officially become a vital medication. The World Health Organization has just added semaglutide—the active ingredient in Ozempic and Wegovy—to its list of essential medicines. The WHO’s Model Lists of Essential Medicines is designed to improve affordability and access for the world’s most impactful drugs. Semaglutide and other GLP-1 drugs are among 20 new additions to the list, and it’s clear why. GLP-1s have completely reshaped how clinicians treat

A Pill to Fight Obesity Is on the Verge of Approval

The next big obesity medication coming down the pipeline will likely come in pill form. Eli Lilly has just released the latest positive Phase III trial results of its experimental oral GLP-1 drug, orforglipron. On Tuesday morning, Eli Lilly reported that orforglipron met the benchmarks of the company’s Phase III ATTAIN-2 study. People taking orforglipron experienced substantial improvements in weight loss and blood sugar control compared to those taking a placebo, the study showed. Armed with d

Ozempic Users Can Now Workout With Apple Fitness Plus Through New Weight-Loss Partnership

If you're a FuturHealth member, you'll now have a free membership to Apple Fitness Plus as part of your program. It's Apple Fitness Plus’s first direct integration with a personalized GLP-1 weight-loss program. FuturHealth offers personalized weight-loss guidance and medications with the help of licensed dietitians and doctors. These include GLP-1 agonists such as semaglutide -- better known as Ozempic. It's partnered with Valisure, a tech company that provides independent quality assurance, to

Apple Fitness Plus Targets Ozempic Users With New Weight-Loss Partnership

If you're a FuturHealth member, you'll now have a free membership to Apple Fitness Plus as part of your program. It's Apple Fitness Plus’s first direct integration with a personalized GLP-1 weight loss program. FuturHealth offers personalized weight loss guidance and medications with the help of licensed dietitians and doctors. These include GLP-1 agonists such as semaglutide -- better known as Ozempic. It's partnered with Valisure, a tech company that provides independent quality assurance, to

Apple Fitness Plus Targets GLP-1 Users With New Weight-Loss Partnership

If you're a FuturHealth member, you'll now have a free membership to Apple Fitness Plus as part of your program. It's Apple Fitness Plus’s first direct integration with a personalized GLP-1 weight loss program. FuturHealth offers personalized weight loss guidance and medications with the help of licensed dietitians and doctors. These include GLP-1 agonists such as semaglutide -- better known as Ozempic. It's partnered with Valisure, a tech company that provides independent quality assurance, to

Doctors Say Ozempic Is Wildly Effective at Helping Addicts Beat Cravings

Image by Getty / Futurism Rx/Medicines Drugs like Ozempic and Wegovy already had a lengthening laundry list of physical health benefits, but now they're increasingly showing promise as treatments for neuropsychological conditions as well. Specifically, one of the most intriguing potential uses for these GLP-1 drugs is in addiction treatment, for vices ranging from alcohol to opioids to stimulants to gambling. And it's gaining momentum: as STAT News reports, one posh Pennsylvania rehabilitation

GLP-1s are breaking life insurance

GPT/GLP-1 Illustration Hello and happy Sunday! Was this newsletter forwarded to you? Sign up to get it in your inbox. I've just got back from HLTH in Amsterdam, nursing what might be the worst three-day hangover of my adult life. Worth it, though. It's one of the best health tech events in Europe, and I made some genuinely great connections. If you’re ever at a large health conference, here’s a neat little hack I learned: Be brave enough to ask questions during panels. It's terrifying, but su

GLP-1s Are Breaking Life Insurance

GPT/GLP-1 Illustration Hello and happy Sunday! Was this newsletter forwarded to you? Sign up to get it in your inbox. I've just got back from HLTH in Amsterdam, nursing what might be the worst three-day hangover of my adult life. Worth it, though. It's one of the best health tech events in Europe, and I made some genuinely great connections. If you’re ever at a large health conference, here’s a neat little hack I learned: Be brave enough to ask questions during panels. It's terrifying, but su

Scientists Gene Hack Mice So Their Livers Produce Their Own Ozempic-Like Drug

Image by Remi Benali/Getty Images Rx/Medicines Scientists have gene-hacked mice to produce their own Ozempic-like drugs — possibly, and provocatively, perhaps paving a path for humans to do so themselves one day. In a new study published in the journal Communications Medicine, researchers from Japan's University of Osaka successfully gene-edited mice livers to produce exenatide, a first-generation diabetes drug and predecessor to now-trendy jabs like Ozempic and Mounjaro. Using lab mice that

These Genetically Modified Mice Make Their Own ‘Ozempic’

The popularity of Ozempic and Wegovy as diabetes and weight loss medications has skyrocketed. But how far would people go to avoid one of their major drawbacks—the need for weekly injections? A study out today shows it’s possible to genetically modify mice to make their own Ozempic-like drugs. Scientists in Japan led the research, which involved gene-editing mice’s livers to produce an internal supply of exenatide, a first-generation GLP-1 drug. The edited mice were able to sustain levels of th

Could Ozempic Treat Migraines, Too? Small Study Finds Early Promise for GLP-1s

Got a blinding headache? Some GLP-1 therapy could surprisingly help. A recent clinical trial has found early evidence that these popular drugs, typically used to treat obesity and type 2 diabetes, may also reduce migraine episodes. Researchers in Italy conducted the small pilot trial, which involved dozens of patients living with obesity and chronic migraine headaches. People experienced a significant drop in the number of migraine days each month upon taking liraglutide, the researchers found—

We’re learning more about what weight-loss drugs do to the body

We know they can suppress appetite, lower blood sugar, and lead to dramatic weight loss. We also know that they come with side effects, which can include nausea, diarrhea, and vomiting. But we are still learning about some of their other effects. On the one hand, these seemingly miraculous drugs appear to improve health in other ways, helping to protect against heart failure, kidney disease, and potentially even substance-use disorders, neurodegenerative diseases, and cancer. But on the other,

Spike in Pancreas Problems From Weight-Loss Drugs Prompts Investigation

Ozempic and similar GLP-1 drugs seem to be hurting some people’s pancreas. UK health officials are planning to study the link between GLP-1 use and acute pancreatitis, following an increase in reported cases this year. The Guardian reported Tuesday that the UK’s Medicines and Healthcare Products Regulatory Agency (MHRA) is launching an investigation into pancreatitis associated with the drug class. Hundreds of residents have complained about pancreas problems after taking semaglutide or other r

Ozempic Might Be a Dementia Buster, Too

Semaglutide, the active ingredient in popular weight loss drugs Ozempic and Wegovy, might also double as a brain booster. Research out today describes a link between semaglutide use and a reduced risk of dementia in people with type 2 diabetes. Scientists at Case Western Reserve University conducted the study, published in the Journal of Alzheimer’s Disease. They found that diabetes patients taking semaglutide have a significantly lower risk of dementia than those taking other diabetes medicati

Novo Nordisk Abruptly Ends Partnership with Hims, Claiming ‘Sham Compounding’ GLP-1 Drugs

Bad blood is brewing among some major players in the weight loss world. Novo Nordisk, the creator of Ozempic and Wegovy, cut short its partnership with telehealth company Hims & Hers Health Inc. over allegations that the latter is still trying to mass-market cheaper versions of the GLP-1 drugs. Bloomberg News reported the abrupt dissolution of the partnership Monday, just two months after it was struck. Novo claims that Hims is using “deceptive marketing” to widely sell compounded semaglutide t

Eli Lilly’s Obesity Pill Appears to Work as Well as Injected GLP-1s

Eli Lilly’s daily anti-obesity pill orforglipron appears to be as good at spurring weight loss and lowering blood sugar in diabetes patients as popular injectable GLP-1 drugs like Ozempic, according to new data from a Phase 3 trial. The results were announced today at the annual meeting of the American Diabetes Association and published in the New England Journal of Medicine. Eli Lilly is the maker of the blockbuster GLP-1 drug tirzepatide, approved as Mounjaro for type 2 diabetes and Zepbound

Surgery Still Beats Ozempic and Other GLP-1 Drugs in Real-World Weight Loss Study

When it comes to weight loss, surgery still reigns supreme. Research out today shows that people undergoing bariatric surgery tend to lose significantly more weight than people taking the newest, most effective GLP-1 medications for obesity. Scientists at New York University conducted the study, which analyzed real-world data from obesity patients. People who received surgery lost five times more weight over a two year span on average than those who were prescribed a GLP-1 drug, they found. The

Doctors Concerned By Massive Uptick In Teens Taking Ozempic

Image by Roberto Pfeil / picture alliance via Getty / Futurism Rx/Medicines Teens are being prescribed Ozempic and similar drugs more than ever before — and some doctors are worried about what the trend could mean. In interviews with Reuters and Raleigh, North Carolina's WRAL, doctors expressed disquiet at recent studies that found that are kids being prescribed the uber-popular jabs at increasing rates. Two recent studies, the first from the from the data firm Truveta and the second from Eve