Deaf Teenager and 24-Year-Old Gain Ability to Hear After Experimental Gene Therapy
In recent years, gene therapy has emerged as a promising treatment for genetic forms of congenital deafness—hearing loss that’s present at birth—in children. A new study shows that gene therapy can bestow hearing in teenagers and adults with this condition, too. The study, published Wednesday in the journal Nature Medicine, recruited patients with deafness or severe hearing impairment caused by mutations in the OTOF gene. This gene manufactures a protein called Otoferlin, which plays a critical