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The Fourth Wave: How Speedballing Is Creating a New Kind of Drug Crisis

Speedballing—the practice of combining a stimulant like cocaine or methamphetamine with an opioid such as heroin or fentanyl—has evolved from a niche subculture to a widespread public health crisis. The practice stems from the early 1900s, when World War I soldiers were often treated with a combination of cocaine and morphine. Once associated with high-profile figures like John Belushi, River Phoenix and Chris Farley, this dangerous polysubstance use has become a leading cause of overdose death