These 20 technologists, entrepreneurs, corporate leaders, and creative thinkers are pushing artificial intelligence in unexpected directions. The biggest story in tech is AI’s increasing capacity to take on tasks once reserved for human beings. But the agents driving that change aren’t machines. They’re humans—inventive, ambitious, enterprising ones. Our third annual roundup of some of the field’s most intriguing players includes scientists and ethicists, CEOs and investors, big-tech veterans and first-time founders. These 20 innovators are tackling challenges from training tomorrow’s AI models to speeding drug discovery to reimagining everyday productivity tools. Household names they’re not. Yet, they’re already changing our world, with much more to come.