Scientists looked at archived hair samples, included these from a baby (right) and an adult (left), to see how much lead they contained.
Humans have found lead useful for thousands of years, but the metal's toxic effects didn't become well known until the 20th century. Now, using historical hair samples, researchers have shown that regulations targeting heavy-metal pollution were extremely effective at reducing the public's exposure to lead once its dangers were known.
"We have hair samples spanning about 100 years," study co-author Ken Smith , a demographer at the University of Utah, said in a statement . The study focused on people living in Utah.
"Back when the regulations were absent," Smith said, "the lead levels were about 100 times higher than they are after the regulations."
In the new study, published Monday (Feb. 2) in the journal PNAS , the researchers detailed their analysis of hair samples from 47 people who lived in the Greater Salt Lake City region as children and as adults. The study participants provided locks of their baby hair that had been preserved in family scrapbooks, as well as a current hair sample. The researchers analyzed the hair for lead using mass spectrometry, a technique that identifies chemical compounds in a sample.
Lead exposure is detrimental to human health , causing damage to the nervous system that can lead to developmental delays, seizures and learning problems, while also raising the risk of fertility issues and high blood pressure . There is no known safe level of lead exposure, the researchers wrote in the study.
A major source of toxic lead exposure in the first half of the 20th century was leaded gasoline. In the 1920s, tetraethyl lead — a compound containing carbon and lead — was added to gasoline to reduce engine "knocking," the pinging sound caused by the premature ignition of fuel. Although the U.S. Public Health Service realized as early as 1925 that leaded gasoline was causing health issues, the fuel additive was not fully banned in the U.S. until 1996.
However, key regulations on lead were established before the 1990s. The U.S. Environmental Protection Agency (EPA), which was created by then-President Richard Nixon in 1970 to address multiple air and pollution problems, resulted in an immediate decline in lead exposure, the researchers found in the new study.
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Concentrations of lead in human hair from the Salt Lake City region were extremely high from 1916 to 1969, in part due to a lack of EPA regulation and in part because of two active lead smelter sites in the area. But from the 1970s to the 1990s, after the EPA was established and the smelting plants were shuttered, the average values declined by two orders of magnitude.
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