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These days, it seems I cannot escape peptides. Online, I’ve been assaulted by videos of shirtless Chads injecting dubiously sourced bottles of the so-called “Wolverine stack.” On the New York City subway, I’m haunted by Serena Williams’ Ro ads for easy GLP-1 access. Silicon Valley seems to be a parade of peptide parties. In Washington, RFK Jr. has said he’s pro-peptide and wants to expand access. In July, the FDA will meet to possibly reclassify 14 peptides so they can be eligible for compounding.
And in Hollywood, Gwyneth Paltrow — mother Goop, one of the original wellness influencers — is selling a series of peptide skincare products. Except, after some research, I’m not sure Paltrow actually understands what peptides are.
You might be wondering why I’m fixating on a Goop product in Optimizer. The short answer: While researching peptides for a forthcoming feature, I’ve descended into madness.
The longer answer is that peptide mania is central to Silicon Valley’s current fixation with longevity and metabolic optimization. As I’ve recently written, wellness trends increasingly inform new health tech features and gadgets that make up the wearable surveillance state. Peptides are also being framed on social media as an innovation that democratizes healthcare. (A similar rhetoric used to describe wearables!) It’s part of the wellness Wild West feedback loop that’s fueling Silicon Valley’s obsession with self-optimization. With that in mind, it’s worth examining how “peptide washing” has crept into various corners of the internet — and the resulting ripple effects.
While peptide shots are a relatively new trend, we’ve known about peptides and how they work for decades. They’re short chains of amino acids, which, in turn, make up proteins. In other words, building blocks for the building blocks. Because a peptide can be a chain ranging from two to roughly 100 amino acids, there are potentially trillions of peptides. Their main function is to act as messengers for various bodily functions. Some are naturally occurring and often come from the foods you eat. Others are made synthetically in a lab. The most famous ones include insulin and GLP-1 medications like semaglutide (Ozempic and Wegovy) and tirzepatide (Zepbound and Mounjaro).
What’s taking social media by storm are peptides that exist in legal gray areas. They’re not widely tested or FDA-approved drugs, and are sometimes sourced from dubious suppliers. I’ve previously written about retatrutide — another popular weight loss peptide — in Optimizer, but there’s a whole slew of others with names that sound vaguely like Star Wars droids. The most popular ones include BPC-157, TB-500, GHK-Cu, and CJC1295. These peptides are touted as biohacks for ailments ranging from fat loss and muscle growth, to faster wound healing, anti-aging, and increased energy. Essentially, everything associated with living a longer, healthier life. Lumped alongside these is NAD+, which is not a peptide but is often marketed as one. That’s partly because it’s frequently consumed as an IV drip and is thus an injectable substance.
But just because you can inject something, that doesn’t make it a peptide.
Do you have experience using peptides? Or extremely strong feelings about this trend? I’m researching this phenomenon and I’d love to chat with you. Hit me up at [email protected] or on Signal at @ vicmsong.14.
NAD stands for nicotinamide adenine dinucleotide. It’s a coenzyme — basically an enzyme booster — that’s found in every cell. Its primary job is to help convert food into energy. It does this by shuttling electrons from one chemical reaction to another. As you age, your NAD levels naturally decline. This can lead to an array of conditions associated with aging, like Type 2 diabetes, lower energy levels, and saggy skin. Not to get too weedsy, but the + in NAD+ simply denotes one of two versions of the NAD molecule. (The other is NADH.)
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