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Can Polymarket predict the progress of science, or are subject-experts better?

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Why This Matters

Prediction markets like Polymarket are gaining traction as tools to forecast scientific and societal outcomes, leveraging collective intelligence to potentially outperform expert predictions. While they offer valuable insights into public perception and probabilistic trends, they are not replacements for scientific expertise or rigorous peer review. Their significance lies in complementing traditional methods, especially in rapidly evolving or uncertain fields.

Key Takeaways

Prediction markets such as Kalshi allow users to speculate on the outcomes of real-world events using cryptocurrency.Credit: Michael Nagle/Bloomberg via Getty

Prediction markets such as Polymarket and Kalshi have soared in popularity over the past few months. From bets on disease outbreaks to wagers about artificial intelligence, many of their markets relate to science and research. So how do Polymarket’s prediction powers compare to the opinions of subject-matter experts?

In prediction markets, users bet on a future event by buying and selling shares in favour of various outcomes. The price of each share is determined neither by expert opinions nor by the ‘house’ setting odds. Rather, prices are based on demand, reflecting the market’s collective belief in the probability of the outcome.

But as well as providing a gambling platform, prediction markets offer a test of the concept of the wisdom of crowds — the long-held idea that collective predictions by large groups of people tend to be better than forecasts by subject specialists. According to Polymarket’s website, prediction markets can often determine outcomes more accurately than experts or polls because “economic incentives ensure market prices adjust to reflect true odds as more knowledgeable participants join”.

Research has found that prediction markets sometimes outperform other forecasting methods in political elections1, but some researchers remain unconvinced that they can rival the work of expert scientists.

Prediction markets are “potentially helpful forecasting supplements” when it comes to science, says Richard Borghesi, who researches finance and prediction markets at the University of South Florida in Tampa. The markets can be useful to gauge how scientific information is received by the public, he says, but they are not “substitutes for models, peer review or expert judgement”, and are less informative when the people trading lack specialist knowledge on the subject.

There are also growing concerns about market manipulation and insider trading on Polymarket and Kalshi. In October last year, Norwegian officials who oversee the Nobel Peace Prize investigated a surge in bets for Venezuelan opposition leader Maria Corina Machado hours before she was awarded the prize.

Possible pandemics

One science-based area in which researchers question the effectiveness of prediction markets’ forecasting is disease outbreaks. When an outbreak of hantavirus was reported on a cruise ship in early May, a Polymarket market predicted a 19% probability of the World Health Organization (WHO) declaring a hantavirus pandemic this year. But that sank after the shock of the initial news; when this article was published, the market sat at a probability of 5%, with about US$14 million in shares traded so far. A similar Kalshi market predicts a 7% chance of the WHO declaring a hantavirus outbreak a public-health emergency of international concern in 2026.

There is no vaccine for deadly hantavirus: what that means for future outbreaks

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