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Privacy risks from medical AI tools are not shared equally

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Why This Matters

This article highlights that powerful medical AI tools can inadvertently reveal sensitive patient information, challenging the assumption that de-identified data remains private. This poses significant privacy risks for patients and underscores the need for more robust data protection measures in healthcare AI development. Ensuring privacy is crucial for maintaining trust and safeguarding personal health information as AI becomes more integrated into medical practice.

Key Takeaways

The use of artificial-intelligence tools in medicine has hinged on an implicit bargain. Patients and health systems permit sensitive records to be used for research, usually after de-identification so that names and other pieces of personal information are removed. In return, researchers and developers create tools that could improve health care, for example by enabling earlier diagnoses and new treatments. This bargain relies on the assumption that it is impossible for people who have access to an AI model to infer information about individuals whose data were used to train it. Writing in Nature, Knolle et al.1 show that, in the context of powerful machine-learning models, this assumption is often untrue.

Nature 656, 42-44 (2026)

doi: https://doi.org/10.1038/d41586-026-02288-9

References Knolle, M. A. et al. Nature 656, 192–198 (2026). Feldman, V. & Chiyuan, Z. In Proc. 34 Int. Conf. Neural Inf. Process. Syst. (eds Larochelle, H. et al.) 2881–2891 (Curran Associates, 2020). Tonekaboni, S., Stempfle, L., Fallahpour, A., Gerych, W. & Ghassemi, M. In Adv. Neural Inf. Process. Syst. 39 (eds Belgrave, D. et al.) 10555–10580 (2026). Geiping, J., Bauermeister, H., Dröge, H. & Moeller, M. In Proc. 34 Int. Conf. Neural Inf. Process. Syst. (eds Larochelle, H. et al.) 16937–16947 (Curran Associates, 2020). Chen, M. et al. In Proc. 2021 ACM SIGSAC Conf. Comput. Commun. Secur. 896–911 (ACM, 2021). Shokri, R., Stronati, M., Song, C. & Shmatikov, V. In Proc. 2017 IEEE Symp. Secur. Priv. (ed. O’Conner, L.) 3–18 (IEEE, 2017). Nissenbaum, H. Wash. Law Rev. 79, 119–157 (2004). Gichoya, J. W. et al. Lancet Digit. Health 4, E406–E414 (2022). Abadi, M. et al. In Proc. 2016 ACM SIGSAC Conf. Comput. Commun. Secur. 308–318 (ACM, 2016). Suriyakumar, V. M., Papernot, N., Goldenberg, A. & Ghassemi, M. In Proc. 2021 ACM Conf. Fairness Account. Transpar. 723–734 (ACM, 2021). Download references

Competing Interests The authors declare no competing interests.

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