Three scientists win 2026 Nobel Prize in Medicine for optogenetics
The Nobel Assembly at Karolinska Institutet awarded the 2026 Nobel Prize in Physiology or Medicine jointly to Karl Deisseroth, Peter Hegemann and Georg Nagel for discoveries on light-gated ion channels and the development of optogenetics. Hegemann and Nagel identified channelrhodopsin, a light-sensitive protein in algae, while Deisseroth turned it into a tool to control nerve cells with light.
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The award recognizes a technique that researchers say let scientists directly manipulate specific neurons and observe resulting changes in behavior, moving neuroscience beyond correlation toward causal explanation of brain function. According to the Nobel committee, this approach has reshaped how memories, emotions and behaviors can be studied in living organisms, suggesting broad implications for understanding neurological and psychiatric conditions.
- Optogenetics uses light to control genetically targeted nerve cells.
- Channelrhodopsin, discovered in algae by Hegemann and Nagel, is the key light-sensitive protein.
- Deisseroth adapted the protein into a practical neuroscience tool now used worldwide.
Source: nobelprize.org, 2026-10-05
Published there as: “Press Release: Nobel Prize in Physiology or Medicine 2026”
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