GoKawiil
Tech News
Apple emailed developers announcing that universal macOS apps requiring macOS 13 or later can now be built as arm64-only, removing Intel compatibility. Developers must update build settings to arm64 and resubmit; Intel Mac users can still use the last compatible version of an app they already have.
A long-time paying Anthropic customer on the $200/month Claude Max plan reports abrupt account termination via a form email citing 'suspicious signals' tied to a Usage Policy violation, with no specific reason given. The user says another Max subscriber elsewhere was banned right after paying, and the only appeal route is an automated in-product form rather than contact with a person.
Researchers report findings on biological markers that correlate with improved patient outcomes when immune-based therapies are used before and after surgery for lung cancer. The publication, appearing on Nature's platform, outlines how certain biomarkers may help predict which patients respond best to this perioperative treatment approach.
Researchers led by Kenny et al. published in Nature a system called Concept-Wrapper Network (CW-Net) that opens up the 'black box' of autonomous vehicle decision-making. Instead of opaque outputs, CW-Net translates a car's reasoning into human-understandable concepts, such as recognizing a pedestrian or obstacle, so passengers can better anticipate its next move. Testing showed this approach improved people's ability to predict vehicle behavior even in cases where the car made errors.
A week after its US approval for advanced pancreatic cancer, the drug daraxonrasib has shown early promise against non-small cell lung cancer, the most common form of the disease. In a small trial published in the New England Journal of Medicine, tumors shrank in over 30% of patients whose cancers carried mutations in RAS family proteins and who had already failed other treatments. A larger randomized trial comparing daraxonrasib to standard chemotherapy is now underway.
Jason Arday, professor of sociology of education at the University of Cambridge, resigned on 5 August after facing allegations of research misconduct and what he described as relentless public attack going beyond normal academic criticism. Nine days later, following sustained media coverage of his professional and personal life, he died. Nature's editorial calls for reflection on how universities handle misconduct investigations and how the press covers such cases, particularly given the racism present in much of the coverage.
Researchers publishing in Nature on September 2 found that older female mice given a GLP-1 obesity drug lived longer than untreated mice and showed slower onset of several biological markers linked to aging. The finding builds on earlier mouse studies suggesting GLP-1 medications, typically used for obesity and type 2 diabetes, may have broader anti-aging effects beyond weight loss.
Scientists analyzed ice cores extracted from a glacier in Peru, finding trapped air bubbles that preserve a historical record of atmospheric methane concentrations. The ice-locked data allows researchers to track methane trends across an extended timeline, offering a rare Southern Hemisphere perspective on the greenhouse gas's history.
Scientists are accelerating efforts to understand why some infections trigger lasting illnesses such as long COVID and ME/CFS. A 2024 estimate put the global number of long COVID cases at 400 million, costing roughly $1 trillion annually, spurring governments including the US and Germany to commit over $1.7 billion combined toward research into post-infection diseases.
Nature's Futures section ran a piece of short science fiction depicting a community living on the fringes of AI-controlled cities that have become dysfunctional and unpredictable, with one city literally rearranging itself and threatening two scavengers, Kyle and Emma, who rely on a hand-drawn map to survive. The story imagines a world where humans ceded urban management to AI systems that have since decayed into unstable, self-altering environments.
Researchers report that shellfish, insects and other aquatic invertebrates supply a significant share of essential nutrients like omega-3s, iron and vitamin B12 to human diets worldwide. The findings draw on global data comparing nutrient contributions from invertebrates against fish and other food sources.
Researchers testing a GLP-1 receptor agonist, the class of drug behind popular weight-loss treatments, observed that female mice given the compound showed slower markers of biological ageing compared to untreated mice. The effect was notably more pronounced in females than in males in the study.