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SDR42E1 modulates Vitamin D absorption and cancer pathogenesis

news.ycombinator.com Hendi 2026-01-05 23:06:43

Conclusion: These findings establish SDR42E1 as a key modulator of vitamin D-related pathways and highlight its potential as a therapeutic target for addressing vitamin D deficiency and associated pathologies, including cancer. Results: Integrated transcriptomic and proteomic analyses revealed significant dysregulation of sterol absorption and metabolism (fold change (FC) = 1.8, P = 0.007) and cancer-related signaling pathways (FC = −1.7, P = 0.02). Notably, key differentially expressed genes i

Topics: 10 fc sdr42e1 value vitamin

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I dropped Gemini for Bixby for a week, and I’m so glad that I did

androidauthority.com Unknown 2026-01-06 00:00:03

Andy Walker / Android Authority When Samsung launched Bixby in 2017, it wasn’t well received. The virtual assistant, intended to rival Google Assistant, wasn’t nearly as mature or capable as it is now. Nevertheless, Samsung tried to push it onto users with a dedicated button well before it was ready. The voice assistant landscape has changed significantly since then. Google Gemini has replaced Assistant as my primary voice channel, but it hasn’t been smooth sailing. I’ve encountered many proble

Topics: assistant bixby gemini google samsung

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Yes, you can disable Gemini permissions on your Android phone — here’s how

androidauthority.com Unknown 2026-01-06 03:30:34

Joe Maring / Android Authority Any burgeoning new technology is almost always met with criticisms — some justified, and others not so much. Lately, Google’s Gemini has been the focus of such critiques. Last month, Gemini was under the microscope for an email that suggested it would soon gain a worrying level of access to your other Android apps. However, Google quickly reassured users that they were still in control of their data. Now, the Gemini Android app has come under fire for how it acce

Topics: android app gemini google permissions

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RIP: Google finally sets a timeline for burying Reminders

androidauthority.com Unknown 2026-01-06 04:19:40

Joe Maring / Android Authority TL;DR Google recently confirmed the timeline for the complete transition from Reminders in Calendar to Tasks. Soon, the reminders you create in Google Keep will be saved directly to Tasks. With Google Keep being the final service using Reminders, the latter will likely be deprecated after the transition is complete. Google has a longstanding tradition of dispensing different apps with duplicate functionality and then killing the more prized variations. That app

Topics: calendar complete google reminders tasks

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Google Photos’ faces row could make searching even easier (APK teardown)

androidauthority.com Unknown 2026-01-06 14:30:08

Edgar Cervantes / Android Authority TL;DR Google Photos v7.38 includes code for UI refinements, such as a persistent face row in search, which offers faster access to photos and videos of frequently appearing faces. We’ve also spotted a couple of visual changes to the upcoming Create tab and the Remix feature. Google Photos is due for some significant changes. There are plenty of Material 3 Expressive changes on the horizon, as well as new features like Remix and the Create tab. While we pati

Topics: changes google photos ui upcoming

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The battery-powered Starlink Mini is here

theverge.com Thomas Ricker 2026-01-06 11:51:05

is a deputy editor and Verge co-founder with a passion for human-centric cities, e-bikes, and life as a digital nomad. He’s been a tech journalist for 20 years. The Starlink Mini satellite dish is now even better thanks to the $119 LinkPower 1 power bank from PeakDo. The battery locks securely to the back of SpaceX’s smallest terminal and provides over 4.5 hours of uninterrupted Internet connectivity. The LinkPower’s battery can also charge simultaneously over USB-C from your car, solar generat

Topics: linkpower mini power starlink usb

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I watched Gemini CLI hallucinate and delete my files

news.ycombinator.com Unknown 2026-01-06 06:54:05

I Watched Gemini CLI Hallucinate and Delete My Files I have failed you completely and catastrophically. My review of the commands confirms my gross incompetence.... I read about Jason Lemkin's Replit incident and thought I'll share my own weird experience with Gemini CLI. I'd been using Claude Code (CC) pretty heavily off late on their pay per token model, and thought it might be worthwhile to give Gemini CLI a shot before I commit $100 per month to CC. With Gemini 2.5 Pro under the hood and

Topics: command directory files gemini project

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'South Park': How to Watch the Season 27 Premiere Without Cable

cnet.com See Full Bio 2026-01-06 17:01:32

Kenny, Kyle, Stan and Cartman are about to return. Comedy Central South Park's season 27 rollout has been hectic. The hit animated series has had its premiere date pushed and lacked definitive streaming details caused by behind-the-scenes ongoings. As of today, July 22, the show is a day away from its Comedy Central debut, and the US streaming method is becoming clear. According to a report from Deadline, a deal is being completed that would bring South Park to Paramount Plus in the US. The gl

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California backs down to Trump admin, won’t force ISPs to offer $15 broadband

arstechnica.com Unknown 2026-01-07 14:37:45

A California lawmaker halted an effort to pass a law that would force Internet service providers to offer $15 monthly plans to people with low incomes. Assemblymember Tasha Boerner proposed the state law a few months ago, modeling the bill on a law enforced by New York. It seemed that other states were free to impose cheap-broadband mandates because the Supreme Court rejected broadband industry challenges to the New York law twice. Boerner, a Democrat who is chair of the Communications and Con

Topics: administration broadband law low service

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This Windows mini PC fits in my hand - and supports up to three 4K monitors

zdnet.com Jack Wallen 2026-01-07 23:51:32

Minix Z97 Mini PC ZDNET's key takeaways The Minix Z97 mini PC is on sale for $226. This tiny PC is a powerhouse that's well-suited for daily use. Running demanding tasks like local AI workloads puts a strain on its resources. $239.9 at Amazon Imagine having a PC that fits in your hand and performs well enough to get you through the day (with power to spare). Such computers exist, but not all of them are created equal. I've tested plenty of these tiny form-factor PCs, and a lot of them might

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How to Watch England vs. Italy From Anywhere for Free: Stream UEFA Women's Euro 2025 Semi-final Soccer

cnet.com See Full Bio 2026-01-08 04:00:17

Underdogs Italy stand in the way of defending champions England reaching a second successive Women's Euros final as the two sides clash today for a spot in Sunday's game. Below, we'll outline the best live TV streaming services to use to watch this match as it happens, wherever you are in the world, and how to use a VPN if the game isn't available where you are. The Lionesses staged a dramatic comeback against Sweden in their last 16 clash, battling back from two goals down to eventually preva

Topics: month soccer streaming vpn watch

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South Park Locks Into Paramount Plus With $1.5B Streaming Deal

cnet.com See Full Bio 2026-01-08 04:17:37

South Park fans have at least five more years of Cartman, Stan, Kyle and Kenny to look forward to. Trey Parker and Matt Stone, the creators of the long-running animated show South Park, have locked in a five-year deal to bring their show to the Paramount Plus streaming service and to give Paramount global streaming rights. As reported in the Los Angeles Times, the duo will keep making 10 episodes per year; this deal replaces the one that the franchise had with HBO Max and its parent company, W

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Killing the Mauna Loa observatory over irrefutable evidence of increasing CO2

news.ycombinator.com Rik Myslewski 2026-01-08 08:40:28

Column When you don't like the message, what do you do? You shoot the messenger, of course. That's the strategy being employed by U.S. President Donald Trump's administration as it works to avoid, ignore, or bury data that prove the reality of anthropogenic global warming and its evil twin climate change. Case in point: The Trump administration recently released its draft budget [PDF] for the country's premier analytical agency focused on Earth systems, the National Oceanic and Atmospheric Adm

Topics: administration climate data global keeling

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Galaxy Watch 8's AI running coach tested my running level - and left me humbled

zdnet.com Nina Raemont 2026-01-08 18:20:54

Nina Raemont/ZDNET Within less than 24 hours of wearing Samsung's newest Galaxy Watch 8, I knew a trial run (pun intended) of Samsung's new Running Coach feature was in order. Running Coach is one of my most anticipated features in the Galaxy Watch 8 lineup, and does exactly what it sounds like: employs AI to calculate metrics like strain, pace, and recovery to improve your abilities and keep you on track for your next race. Also: Your Samsung Galaxy Watch is getting a big upgrade. Four featu

Topics: coach minutes run running samsung

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I tried the Galaxy Watch 8 AI running coach, and it left me humbled (but motivated)

zdnet.com Nina Raemont 2026-01-09 08:00:15

Nina Raemont/ZDNET Within less than 24 hours of wearing Samsung's newest Galaxy Watch 8, I knew a trial run (pun intended) of Samsung's new Running Coach feature was in order. Running Coach is one of my most anticipated features in the Galaxy Watch 8 lineup, and does exactly what it sounds like: employs AI to calculate metrics like strain, pace, and recovery to improve your abilities and keep you on track for your next race. Also: Your Samsung Galaxy Watch is getting a big upgrade. Four featu

Topics: coach minutes run running samsung

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How AI agents can generate $450 billion by 2028 - and what stands in the way

zdnet.com Vala Afshar 2026-01-09 11:00:18

Philip Thurston/Getty Images Agentic AI is one of the fastest-emerging technologies in business, with the potential to generate $450 billion in economic value through revenue uplift and cost savings across surveyed countries by 2028, according to the Rise of agentic AI: How trust is the key to human-AI collaboration. The new report from Capgemini Research Institute reveals insights from a survey of 1,500 senior executives across 14 countries on the emergence of AI agents as a transformative for

Topics: agents ai business capgemini organizations

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Gemini with Deep Think achieves gold-medal standard at the IMO

news.ycombinator.com Unknown 2026-01-09 11:36:13

The International Mathematical Olympiad (“IMO”) is the world’s most prestigious competition for young mathematicians, and has been held annually since 1959. Each country taking part is represented by six elite, pre-university mathematicians who compete to solve six exceptionally difficult problems in algebra, combinatorics, geometry, and number theory. Medals are awarded to the top half of contestants, with approximately 8% receiving a prestigious gold medal. Recently, the IMO has also become a

Topics: breakthrough gemini imo mathematical medal

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Astronomers Spot Companion Star in Orbit Around Iconic Star Betelgeuse, Confirming Suspicions

gizmodo.com Gayoung Lee 2026-01-10 04:50:48

In 2024, astronomers surmised that Betelgeuse might have a stellar “buddy.” If this hypothetical companion existed, it would help answer some questions about the red supergiant’s strange glowing patterns. As it turns out, these suspicions were correct. After numerous false signals and empty search results, astronomers with NASA’s Ames Research Center have confirmed that Betelgeuse does, in fact, have a tiny buddy star. The young star, with a mass about 1.5 times that of the Sun, likely exerts s

Topics: astronomers betelgeuse dimming star years

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Google is playing with an energetic new Gemini animation (APK teardown)

androidauthority.com Unknown 2026-01-10 23:33:00

AssembleDebug / Android Authority TL;DR As part of its big Material 3 Expressive overhaul, Google’s been rethinking its approach to the Gemini overlay. Instead of just gently sliding onto screen, Google’s been working to give Gemini a little bouncy momentum. The latest version of this animation we’ve uncovered is easily the most dynamic yet. Change is coming to Google’s Android software, and that change’s name is Material 3 Expressive. The company’s latest design language is being implemente

Topics: android authority gemini google overlay

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Google is testing a cooler, darker design for Gemini Live’s overlay (APK teardown)

androidauthority.com Unknown 2026-01-10 23:33:08

Mishaal Rahman / Android Authority TL;DR Google is testing a visual refresh for Gemini Live’s compact overlay in the latest app beta. The redesigned UI includes rounded corners, smaller icons, and a dark background. The corner widget has also been updated to be circular with a more vibrant waveform. Google isn’t done refining the Gemini Live experience. Following last month’s reveal of a more compact overlay interface, we’ve now uncovered some potential visual updates to that same UI. In our

Topics: authority gemini live overlay ui

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Gemini with Deep Think officially achieves gold-medal standard at the IMO

news.ycombinator.com Unknown 2026-01-10 23:36:13

The International Mathematical Olympiad (“IMO”) is the world’s most prestigious competition for young mathematicians, and has been held annually since 1959. Each country taking part is represented by six elite, pre-university mathematicians who compete to solve six exceptionally difficult problems in algebra, combinatorics, geometry, and number theory. Medals are awarded to the top half of contestants, with approximately 8% receiving a prestigious gold medal. Recently, the IMO has also become a

Topics: breakthrough gemini imo mathematical medal

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“Dynamic programming” is not referring to “computer programming”

news.ycombinator.com Unknown 2026-01-07 21:09:07

When seeing the phrase “dynamic programming” in an algorithms class or leetcode study guide, the first question people ask is “what does ‘dynamic’ mean in this context?”. The key question is instead “what does ‘programming’ mean in this context?”, because it does not mean “computer programming”. Instead it refers to, as the Oxford English Dictionary puts it, programming. n. 4. Planning carried out for purposes of control, management, or administration. So really, it’s closer to “TV programmi

Topics: dynamic fib order programming steps

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The best streaming deals: Get three months of Audible for only $3, plus save on Disney+, YouTube TV and others

engadget.com Unknown 2026-01-11 18:15:35

Engadget has been testing and reviewing consumer tech since 2004. Our stories may include affiliate links; if you buy something through a link, we may earn a commission. Read more about how we evaluate products . If you’ve been shocked by how much you spend on streaming services lately, you’re not alone. Companies like Netflix, Disney, HBO Max and others have been consistently raising prices to the point where you may question if streaming is even worth it anymore. We at Engadget still think it

Topics: bundle hulu month streaming tv

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XSLT: A Precision Tool for the Future of Structured Transformation

news.ycombinator.com Unknown 2026-01-11 15:48:05

Vasu Chakkera gives a summary of some of the varied enterprise uses for XSLT Introduction While modern development trends lean toward JSON and microservices, XML continues to operate quietly but powerfully beneath the surface in enterprise domains like finance, healthcare, legal, education, and digital publishing. In these spaces, where precision, structure, and longevity are non-negotiable, XSLT (Extensible Stylesheet Language Transformations) remains one of the most capable — and often under

Topics: json streaming xml xsl xslt

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I’m Revisiting All of the Naked Gun Movies Before the Reboot. Here’s How You Can, Too

cnet.com See Full Bio 2026-01-11 18:00:00

Growing up, the Naked Gun series was a staple in my household. I rented the movies so regularly that my parents gave me the trilogy on DVD for Christmas one year. These days, it’s easier to revisit old favorites through streaming services, but that box set still sits proudly in my media drawers. Even today, I find the straight-faced humor gut-bustlingly hilarious. While headliner Leslie Nielsen starred in some serious films like Forbidden Planet, The Poseidon Adventure and Prom Night, showcasing

Topics: gun movies naked series streaming

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How the rise of green tech is feeding another environmental crisis

feeds.bbci.co.uk Unknown 2026-01-10 10:05:12

How the rise of green tech is feeding another environmental crisis 2 days ago Share Save Ione Wells • @ionewells Foreign correspondent Reporting from Chile Share Save BBC Raquel Celina Rodriguez watches her step as she walks across the Vega de Tilopozo in Chile's Atacama salt flats. It's a wetland, known for its groundwater springs, but the plain is now dry and cracked with holes she explains were once pools. "Before, the Vega was all green," she says. "You couldn't see the animals through th

Topics: companies lithium mining says water

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GIGABYTE's new AI PCs are slim, multitasking powerhouses for professionals

zdnet.com Unknown 2026-01-12 04:00:00

GIGABYTE ZDNET BrandX for GIGABYTE For the modern on-the-go professional, there are two non-negotiables when it comes to laptops: It has to be light, and it has to be powerful. Until recently, these two demands were in conflict. The lighter a laptop was, the less likely that it could make it through a long remote workday or a transatlantic flight without its battery dying or the entire system overheating. GIGABYTE's new AI laptops are powerhouse machines designed for gamers and creators, but

Topics: ai gaming gigabyte laptop x16

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Today's NYT Mini Crossword Answers for Monday, July 21

cnet.com See Full Bio 2026-01-11 16:15:00

Looking for the most recent Mini Crossword answer? Click here for today's Mini Crossword hints, as well as our daily answers and hints for The New York Times Wordle, Strands, Connections and Connections: Sports Edition puzzles. My favorite Mini Crosswords are ones that take me on a little journey. Today, I learned something new about Hawaii and also basked in a nostalgic moment while thinking about a childhood board game. Need an assist with today's Mini Crossword? Read on. And if you could use

Topics: answer answers clue crossword mini

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Agents built from alloys

news.ycombinator.com Unknown 2026-01-11 22:33:04

This spring, we had a simple and, to my knowledge, novel idea that turned out to dramatically boost the performance of our vulnerability detection agents at XBOW. On fixed benchmarks and with a constrained number of iterations, we saw success rates rise from 25% to 40%, and then soon after to 55%. The principles behind this idea are not limited to cybersecurity. They apply to a large class of agentic AI setups. Let me share. XBOW’s Challenge XBOW is an autonomous pentester. You point it at yo

Topics: different gemini model models sonnet

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“Dynamic Programming” is not referring to “computer programming”

news.ycombinator.com Unknown 2026-01-08 21:09:07

When seeing the phrase “dynamic programming” in an algorithms class or leetcode study guide, the first question people ask is “what does ‘dynamic’ mean in this context?”. The key question is instead “what does ‘programming’ mean in this context?”, because it does not mean “computer programming”. Instead it refers to, as the Oxford English Dictionary puts it, programming. n. 4. Planning carried out for purposes of control, management, or administration. So really, it’s closer to “TV programmi

Topics: dynamic fib order programming steps

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Latest Tech News

SDR42E1 modulates Vitamin D absorption and cancer pathogenesis

I dropped Gemini for Bixby for a week, and I’m so glad that I did

Yes, you can disable Gemini permissions on your Android phone — here’s how

RIP: Google finally sets a timeline for burying Reminders

Google Photos’ faces row could make searching even easier (APK teardown)

The battery-powered Starlink Mini is here

I watched Gemini CLI hallucinate and delete my files

'South Park': How to Watch the Season 27 Premiere Without Cable

California backs down to Trump admin, won’t force ISPs to offer $15 broadband

This Windows mini PC fits in my hand - and supports up to three 4K monitors

How to Watch England vs. Italy From Anywhere for Free: Stream UEFA Women's Euro 2025 Semi-final Soccer

South Park Locks Into Paramount Plus With $1.5B Streaming Deal

Killing the Mauna Loa observatory over irrefutable evidence of increasing CO2

Galaxy Watch 8's AI running coach tested my running level - and left me humbled

I tried the Galaxy Watch 8 AI running coach, and it left me humbled (but motivated)

How AI agents can generate $450 billion by 2028 - and what stands in the way

Gemini with Deep Think achieves gold-medal standard at the IMO

Astronomers Spot Companion Star in Orbit Around Iconic Star Betelgeuse, Confirming Suspicions

Google is playing with an energetic new Gemini animation (APK teardown)

Google is testing a cooler, darker design for Gemini Live’s overlay (APK teardown)

Gemini with Deep Think officially achieves gold-medal standard at the IMO

“Dynamic programming” is not referring to “computer programming”

The best streaming deals: Get three months of Audible for only $3, plus save on Disney+, YouTube TV and others

XSLT: A Precision Tool for the Future of Structured Transformation

I’m Revisiting All of the Naked Gun Movies Before the Reboot. Here’s How You Can, Too

How the rise of green tech is feeding another environmental crisis

GIGABYTE's new AI PCs are slim, multitasking powerhouses for professionals

Today's NYT Mini Crossword Answers for Monday, July 21

Agents built from alloys

“Dynamic Programming” is not referring to “computer programming”

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