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How the Alzheimer's Research Scandal Set Back Treatment 16 Years (2022)

news.ycombinator.com Unknown 2026-03-19 04:53:13

In 2006, a landmark study in Nature identified a possible cause of Alzheimer’s disease. For almost 16 years, this study influenced how scientists approached Alzheimer’s and how major research grants were given. But in the summer of 2022, the editors of Nature issued a chilling disclaimer. There was concern regarding the images that accompanied the article. An investigation was underway, and readers were urged to “use caution” when relying on the results. A whistleblower had come forward and sa

Topics: alzheimer amyloid hypothesis research schrag

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The Best ‘Final Fantasy’ References in Its Huge ‘Magic: The Gathering’ Crossover

gizmodo.com James Whitbrook 2026-03-19 06:00:23

Today one of the biggest sets in Magic: The Gathering‘s recent history makes its grand arrival at last: Final Fantasy, the first of Magic‘s at-times-controversial “Universes Beyond” crossovers with other franchises to be given the full standard-legal treatment. It’s a marriage of two of gaming’s most beloved fantasy realms, and with absolute legions of fans of both Magic and Final Fantasy to please, it has to hit the highlights and mechanical flavoring of 16 mainline game’s worth of viable cards

Topics: card fantasy final magic player

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How the Alzheimer's Research Scandal Set Back Treatment 16 Years

news.ycombinator.com Unknown 2026-03-19 14:53:13

In 2006, a landmark study in Nature identified a possible cause of Alzheimer’s disease. For almost 16 years, this study influenced how scientists approached Alzheimer’s and how major research grants were given. But in the summer of 2022, the editors of Nature issued a chilling disclaimer. There was concern regarding the images that accompanied the article. An investigation was underway, and readers were urged to “use caution” when relying on the results. A whistleblower had come forward and sa

Topics: alzheimer amyloid hypothesis research schrag

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MUMPS

news.ycombinator.com Unknown 2026-03-19 14:52:34

Programming language This article is about the programming language. For the disease, see Mumps . For other uses, see Mumps (disambiguation) MUMPS ("Massachusetts General Hospital Utility Multi-Programming System"), or M, is an imperative, high-level programming language with an integrated transaction processing key–value database. It was originally developed at Massachusetts General Hospital for managing patient medical records and hospital laboratory information systems. MUMPS technology ha

Topics: 11 language mumps set standard

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You Can Tell When War Is Breaking Out Because the Pentagon's Pizza Orders Spike Drastically

futurism.com Unknown 2026-03-19 17:10:53

You Can Tell When War Is Breaking Out Because the Pentagon's Pizza Orders Spike Drastically "Who says pie charts aren't useful?" Pizza Premonition A flurry of activity at pizza delivery outlets near the Pentagon in Arlington, Virginia, is a surprisingly accurate predictor of war, as hungry military leadership hunkers down to monitor unfolding military activities. As painstakingly documented by X account Pentagon Pizza Report, a "busier than usual" indicator on the Google Maps profile of the

Topics: just military pentagon pizza war

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The case for embedding audit trails in AI systems before scaling

venturebeat.com Emilia David 2026-03-19 19:13:09

Join the event trusted by enterprise leaders for nearly two decades. VB Transform brings together the people building real enterprise AI strategy. Learn more Editor’s note: Emilia will lead an editorial roundtable on this topic at VB Transform this month. Register today. Orchestration frameworks for AI services serve multiple functions for enterprises. They not only set out how applications or agents flow together, but they should also let administrators manage workflows and agents and audit t

Topics: agents ai enterprises orchestration systems

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iPhone XS now vintage, here’s what that means for repair and support

9to5mac.com Marcus Mendes 2026-03-19 19:17:44

Apple has officially added the iPhone XS to its list of vintage products, marking the end of an era for one of the more iterative chapters in the iPhone’s history. Here’s what that means if you’re still rocking yours. Last November, Apple added the iPhone XS Max to its vintage list. And today, as noted by Macrumors’ Joe Rossignol, the device’s junior sibling has also officially joined the club. Apple classifies a device as “vintage” once five years have passed since it stopped being sold by of

Topics: added apple iphone list vintage

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AirTag helps London couple recover stolen car after police refuse to act

9to5mac.com Marcus Mendes 2026-03-19 19:55:08

A London couple was able to locate and reclaim their Jaguar E-Pace this week using Apple’s AirTag, after local police chose not to take immediate action, even with real-time location data in hand. As reported by BBC News, the £46,000 stolen vehicle was taken from outside the couple’s home in Brook Green, Hammersmith, on June 3. The car had an AirTag hidden inside, which allowed the owners to track its precise location to a nearby neighborhood in Chiswick. The couple contacted the Metropolitan

Topics: airtag car couple location police

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AI agents will be ambient, but not autonomous - what that means for us

zdnet.com Sabrina Ortiz 2026-03-19 19:15:35

Harrison Chase, LangChain CEO and co-founder, takes the stage at Cisco Live! to discuss ambient agents. Sabrina Ortiz/ZDNET Until recently, AI solutions that can execute tasks on your behalf seemed futuristic. Now the era of AI agents is here, with nearly every company offering its own solution. On the horizon, though, is a more advanced and even more promising milestone -- ambient agents. On day three of the Cisco Live! conference, LangChain CEO and co-founder Harrison Chase took the stage to

Topics: agents ai ambient chase human

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Mumps (Programming Language)

news.ycombinator.com Unknown 2026-03-19 19:52:34

Programming language This article is about the programming language. For the disease, see Mumps . For other uses, see Mumps (disambiguation) MUMPS ("Massachusetts General Hospital Utility Multi-Programming System"), or M, is an imperative, high-level programming language with an integrated transaction processing key–value database. It was originally developed at Massachusetts General Hospital for managing patient medical records and hospital laboratory information systems. MUMPS technology ha

Topics: 11 language mumps set standard

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Magic Cue on the Pixel 10 sounds like Pixel Screenshots on steroids

androidauthority.com Unknown 2026-03-20 06:19:41

Joe Maring / Android Authority TL;DR Google has reportedly been working on a new AI-powered assistance tool for Pixel devices since 2023. The system would monitor your screen and actions in apps, and offer “personal predictive suggestions.” First known as Pixie, and then Pixel Sense, a new leak suggests Google has renamed the tool to Magic Cue. Who doesn’t love a good mystery? In the smartphone world, upcoming high-profile devices sometimes leak so much that it feels like there’s nothing lef

Topics: cue google magic pixel sense

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Google links massive cloud outage to API management issue

bleepingcomputer.com Unknown 2026-03-20 06:39:02

Google says an API management issue is behind Thursday's massive Google Cloud outage, which disrupted or brought down its services and many other online platforms. Google says the cloud outage started around 10:49 ET and ended at 3:49 ET, after causing issues for millions of users worldwide for over three hours. Besides Google Cloud, the incident also impacted Gmail, Google Calendar, Google Chat, Google Cloud Search, Google Docs, Google Drive, Google Meet, Google Tasks, Google Voice, Google Le

Topics: cloud cloudflare google outage services

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Subtype Inference by Example

news.ycombinator.com Considerations On Codecrafting 2026-03-16 13:04:40

In recent years, there has been increasing interest in tools and programming languages that can automatically detect common types of bugs, in order to improve product quality and programmer productivity. Most commonly, this is done via static type systems, but traditional static type systems require large amounts of manual annotation by programmers, making them difficult to work with. Therefore, modern programming languages make increasing use of type inference, which provides the same benefits

Topics: cubiml languages let syntax type

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Beyond Bluesky: These are the apps building social experiences on the AT Protocol

techcrunch.com Sarah Perez 2026-03-20 06:04:43

A year ago, Bluesky was opening up to the public and was known as one of the many X competitors that emerged after Elon Musk acquired the network formerly known as Twitter. Today, Bluesky’s social network has grown to over 36.5 million users, while the technology it’s built upon — the AT Protocol (or ATProto for short) — is being used to develop dozens more applications designed to work together as part of an open social web. The developers behind many of these apps attended the first conferenc

Topics: app bluesky credits image social

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The cloud broke Thursday and it'll happen again - how to protect your business before then

zdnet.com Steven Vaughan-Nichols 2026-03-20 10:54:00

Akaradech Pramoonsin/Getty Images After a rocky Thursday afternoon on the internet, both Google and Cloudflare services appear to be operating normally as of Friday morning. When trouble started, the question wasn't what's wrong with what cloud service; it was, what service isn't down? Also: The best cloud storage services of 2025: Expert tested What happened on Thursday? First, this was not just an American problem. Google Cloud reported that it was a global problem. Google stated that mult

Topics: cloud cloudflare google outage services

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This Anker MagSafe iPhone Charger That Doubles as a Stand Hits All-Time Low, Part of Father’s Day Deals

gizmodo.com Joe Tilleli 2026-03-20 10:40:55

Time is running of to find the right gift for your Dad. This weekend is Father’s Day so if you’re still on the hunt for something practical to show your love that you just know your dad will appreciate, consider this. This deal on the Anker 633 magnetic battery could be your saving grace. Check if your dad has a new enough phone that supports magnetic wireless charging, then get him this charging stand that’s down 33% right now. You can scoop it up for just $40. Anker is really firing on all cy

Topics: battery charger magnetic phone stand

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The founder experience at TechCrunch All Stage: Built for people building what’s next

techcrunch.com Techcrunch Events 2026-03-20 10:05:00

For a founder, time is the one resource you can’t raise. That’s why TechCrunch All Stage — happening July 15 in Boston’s SoWa Power Station — is designed to make every minute count. Whether you’re at the whiteboard sketching v1 of your product or figuring out how to lead a team of 50, TechCrunch All Stage meets you where you are — and gives you the access, insight, and connections to move forward faster. Plus, you can get a $210 discount on your ticket right now, if you move quickly. The day d

Topics: day pitch stage techcrunch ventures

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Ask HN: Is ageism in tech still a problem?

news.ycombinator.com Unknown 2026-03-20 15:08:30

Well, it's been a while since I touched this theme. 6 years ago, I launched a job board trying to fight ageism in tech (https://news.ycombinator.com/item?id=20252097) It did super well in terms of upvotes and comments but not $ speaking (made $0) This seems to be a current problem but what's the solution?

Topics: 20252097 ageism ago board com

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Design Patterns for Securing LLM Agents Against Prompt Injections

news.ycombinator.com Simon Willison 2026-03-20 17:27:46

Design Patterns for Securing LLM Agents against Prompt Injections This new paper by 11 authors from organizations including IBM, Invariant Labs, ETH Zurich, Google and Microsoft is an excellent addition to the literature on prompt injection and LLM security. In this work, we describe a number of design patterns for LLM agents that significantly mitigate the risk of prompt injections. These design patterns constrain the actions of agents to explicitly prevent them from solving arbitrary tasks.

Topics: agent agents llm pattern prompt

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If You Own an Xbox Series X/S, You Can Buy an Official 2TB Expansion Card for 40% Off on Amazon

gizmodo.com Gizmodo Deals 2026-03-20 18:25:12

If you own an Xbox Series X or S, you’re already aware of how quickly your storage fills up with new games. Expansions are inevitable and the Seagate Expansion Card SSD is designed specifically for these Microsoft consoles which makes it perfect for gamers who want to maintain their library within reach without sacrificing performance. Amazon currently has this must-have accessory on sale for a low of $219, down from a list price of $360. That’s a 39% discount (just barely within Black Friday t

Topics: card expansion games storage xbox

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Best Packing Cubes for Every Kind of Trip (2025), Tested and Reviewed

wired.com Kat Merck 2026-03-20 22:02:00

Other Packing Cubes We Tried GoRuck Packing Cube for $25 (for 1, 10L flat): I loved the 15 x 10 x 3-inch size I tested of this rugged, 200-denier nylon cube with a mesh front. It fit almost anything I needed for any occasion, with a convenient carry handle and signature GoRuck American flag patch on the front. However, they are pricey, and unless you need them to match your GoRuck gear, there's nothing about them that stands out above comparably priced cubes. Amazon Basics for $16 (set of 4):

Topics: bag cubes like packing set

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AirTag 2 Rumors: The Most Recent Leaks and What They Mean

cnet.com See Full Bio 2026-03-21 01:45:02

It's been more than four years since Apple launched the original AirTag. In Apple years, that's practically a lifetime. While the little tracker has become a go-to for finding lost keys, wallets and luggage, it is severely overdue for an update. That sort of delay is unusual for Apple, which tends to refresh most of its product lines every couple of years. Now, as we head into summer travel season, when item trackers are more useful than ever, rumors and hints are heating up that a second-gen A

Topics: airtag apple finding new tracking

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What to expect at TechCrunch All Stage: One day, countless connections and takeaways

techcrunch.com Techcrunch Events 2026-03-21 02:01:00

Whether you’re a founder gearing up for your next raise or a VC scouting your next portfolio win, TechCrunch All Stage, happening July 15 at Boston’s SoWa Power Station, packs more into one day than most multi-day conferences manage to deliver. This isn’t your typical sit-and-listen event. It’s designed to help you build momentum in real time — whether that means raising capital, sharpening your pitch, expanding your network, or rethinking your go-to-market. And for a limited time, tickets are

Topics: day stage techcrunch vc ventures

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Cloudflare: Outage not caused by security incident, data is safe

bleepingcomputer.com Unknown 2026-03-21 11:09:24

Cloudflare has confirmed that the massive service outage yesterday was not caused by a security incident and no data has been lost. The issue has been largely mitigated. It started 17:52 UTC yesterday when the Workers KV (Key-Value) system went completely offline, causing widespread service losses across multiple edge computing and AI services. Workers KV is a globally distributed, consistent key-value store used by Cloudflare Workers, the company’s serverless computing platform. It is a funda

Topics: cloudflare failure kv storage workers

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Show HN: GetHooky – a language-agnostic Git hook manager

news.ycombinator.com Unknown 2026-03-21 08:31:44

The art of forgetting to run the linter isn't old - wise old programmer, 2025 Ever forgot to run the linter before doing a git push to production? Not anymore! GetHooky will make sure you don't screw up again! Automatically test and lint your code upon doing a commit or git push! Most tools for git hook mangement are mostly language specific and work for specific languages only, or you either have to do crazy configurations. But with GetHooky, all you have to do is, install once, use as ma

Topics: gethooky git language linter work

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SAG-AFTRA board approves agreement with game companies on AI and new contract

venturebeat.com Dean Takahashi 2026-03-21 11:04:00

The Screen Actors Guild-American Federation of Television and Radio Artists (SAG-AFTRA) National Board approved the tentative agreement with the video game bargaining group. The contract on terms for the Interactive Media Agreement will now be submitted to the membership for ratification. The new contract accomplishes important guardrails and gains around AI, including the requirement of informed consent across various AI uses and the ability for performers to suspend informed consent for Digi

Topics: aftra agreement performers ratification video

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Cloud collapse: Replit and LlamaIndex knocked offline by Google Cloud identity outage

venturebeat.com Emilia David 2026-03-21 18:05:33

Join the event trusted by enterprise leaders for nearly two decades. VB Transform brings together the people building real enterprise AI strategy. Learn more Days after OpenAI and Google Cloud announced a partnership to support the growing use of generative AI platforms, much of the AI-powered web and tools went down due to an outage of the leading cloud providers. Google Cloud Service Platform (GCP) and some Cloudflare services began experiencing issues around 10:00 a.m. PT today, affecting s

Topics: ai cloud google outage services

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Instagram May Soon Let You Rearrange Your Grid. What to Know

cnet.com See Full Bio 2026-03-21 17:51:00

If you like to keep your Instagram profile as more of a personal photo album and less of a public bulletin board, Instagram's upcoming feature is for you. Instagram will let users quietly post to your profile without broadcasting it to your followers, the company said on Thursday. Instagram also said it would let you rearrange your profile grid. It's not clear how either feature will work yet. Static posts and Reels have historically appeared in chronological order on Instagram, so this could o

Topics: feature flexibility instagram profile said

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Coming to Apple OSes: A seamless, secure way to import and export passkeys

arstechnica.com Unknown 2026-03-22 02:26:28

Apple this week provided a glimpse into a feature that solves one of the biggest drawbacks of passkeys, the industry-wide standard for website and app authentication that isn't susceptible to credential phishing and other attacks targeting passwords. The import/export feature, which Apple demonstrated at this week’s WWDC 25, will be available in the next major releases of iOS, macOS, iPadOS, and visionOS. It aims to solve one of the biggest shortcomings of passkeys as they have existed to date.

Topics: apple credential device manager passkeys

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Google cloud and other internet services are reporting outages

cnbc.com Jennifer Elias 2026-03-22 07:31:03

A visitor walks past a Google Cloud sign at the booth of Google during the Hanover technology Fair (Hannover Messe) on April 22, 2024 in Hanover, northern Germany, with Norway as partner country. Google's cloud was suffering from global outages on Thursday, as were other cloud-based services. Users on social media reported that several major internet services were experiencing disruptions due to Google cloud platforms. "We are experiencing service issues with multiple GCP products," a status

Topics: cloud google page services web

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Latest Tech News

How the Alzheimer's Research Scandal Set Back Treatment 16 Years (2022)

The Best ‘Final Fantasy’ References in Its Huge ‘Magic: The Gathering’ Crossover

How the Alzheimer's Research Scandal Set Back Treatment 16 Years

MUMPS

You Can Tell When War Is Breaking Out Because the Pentagon's Pizza Orders Spike Drastically

The case for embedding audit trails in AI systems before scaling

iPhone XS now vintage, here’s what that means for repair and support

AirTag helps London couple recover stolen car after police refuse to act

AI agents will be ambient, but not autonomous - what that means for us

Mumps (Programming Language)

Magic Cue on the Pixel 10 sounds like Pixel Screenshots on steroids

Google links massive cloud outage to API management issue

Subtype Inference by Example

Beyond Bluesky: These are the apps building social experiences on the AT Protocol

The cloud broke Thursday and it'll happen again - how to protect your business before then

This Anker MagSafe iPhone Charger That Doubles as a Stand Hits All-Time Low, Part of Father’s Day Deals

The founder experience at TechCrunch All Stage: Built for people building what’s next

Ask HN: Is ageism in tech still a problem?

Design Patterns for Securing LLM Agents Against Prompt Injections

If You Own an Xbox Series X/S, You Can Buy an Official 2TB Expansion Card for 40% Off on Amazon

Best Packing Cubes for Every Kind of Trip (2025), Tested and Reviewed

AirTag 2 Rumors: The Most Recent Leaks and What They Mean

What to expect at TechCrunch All Stage: One day, countless connections and takeaways

Cloudflare: Outage not caused by security incident, data is safe

Show HN: GetHooky – a language-agnostic Git hook manager

SAG-AFTRA board approves agreement with game companies on AI and new contract

Cloud collapse: Replit and LlamaIndex knocked offline by Google Cloud identity outage

Instagram May Soon Let You Rearrange Your Grid. What to Know

Coming to Apple OSes: A seamless, secure way to import and export passkeys

Google cloud and other internet services are reporting outages

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