Researchers introduce RetroChimera, a retrosynthesis model that combines two neural architectures with different inductive biases through a learned ensembling method. It outperforms existing baseline models across varying data scales and generalizes well even with limited examples per reaction type. In blind evaluations, professional chemists preferred RetroChimera's suggested synthesis routes over both published reference reactions and predictions from other AI systems.
A reader without formal computer science training describes spending a year using LLMs to build a complex TypeScript/JavaScript system with APIs, PostgreSQL, and multi-model AI pipelines. When trying to move the project to production, they found themselves stuck fixing cascading errors they didn't fully understand, realizing the system's complexity had outpaced their own comprehension. A programming writer responds publicly to the reader's letter, offering candid, non-definitive thoughts on learning and competence in an AI-assisted coding era.
Microsoft is adding automated AI checks to its Edge extension review pipeline as vibe-coding tools drive a sharp rise in add-on submissions. The AI will handle repeatable validation checks and flag common security issues, while human reviewers focus on more complex cases.
Hiring Lab data shows software engineering job postings have risen 15% since 2025, with 71% of that growth concentrated in roles for experienced engineers who now also oversee AI-assisted development work. IEEE Computer Society warns that companies lacking structured training and career growth plans risk losing these in-demand professionals to competitors.
Amazon has cut the price of Samsung's new Freestyle Plus portable projector by $250, from its $1,197.99 list price to $947.99, a 21% reduction. This marks the first time the device has been discounted since its release, and it's the best offer seen on it so far this year.
Adobe introduced AI Assisted Editor, a new Photoshop interface that lets users edit images through natural language prompts alongside the existing Pro Editor workspace. The company also unveiled a light adjustment layer, Instruct Edit with Masks, and a Markup tool for drawing edit instructions directly on images. These features are currently available in the $23-per-month Photoshop beta.
Adobe has introduced a beta feature called AI Assisted Editor, an optional Photoshop mode that swaps the app's traditional tool-heavy interface for a simplified, natural-language editing experience. The mode bundles Firefly-powered tools like Prompt to Edit, Generative Fill, Generative Expand, Remove Background, and a new AI Markup tool that lets users sketch or click on an image and describe changes in plain text. Users can toggle between this mode and Photoshop's standard Pro Editor at any time.
Billionaire investor Stanley Druckenmiller published a Wall Street Journal op-ed criticizing Treasury Secretary Scott Bessent, and readers quickly flagged telltale AI-generated phrasing using detection tools like Pangram. Druckenmiller confirmed he used AI to draft the piece, comparing it to using a calculator, and WSJ opinion editor Paul Gigot backed the decision not to disclose AI assistance, calling AI use a 'fact of modern life.'
GoKawiil