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One universal antiviral to rule them all?

For a few dozen people in the world, the downside of living with a rare immune condition comes with a surprising superpower—the ability to fight off all viruses. Columbia immunologist Dusan Bogunovic discovered the individuals’ antiviral powers about 15 years ago, soon after he identified the genetic mutation that causes the condition. At first, the condition only seemed to increase vulnerability to some bacterial infections. But as more patients were identified, its unexpected antiviral benef

One Universal Antiviral to Rule Them All?

For a few dozen people in the world, the downside of living with a rare immune condition comes with a surprising superpower—the ability to fight off all viruses. Columbia immunologist Dusan Bogunovic discovered the individuals’ antiviral powers about 15 years ago, soon after he identified the genetic mutation that causes the condition. At first, the condition only seemed to increase vulnerability to some bacterial infections. But as more patients were identified, its unexpected antiviral benef

Scientists Create Ultimate Antiviral Using Rare "Superpower" Genetic Mutation

Image by Getty / Futurism Genetics A rare genetic mutation that causes a deficiency in an immune regulator called ISG15 is known to make people more vulnerable to some bacterial infections and cause persistent inflammation — but it can unlock some unexpected antiviral "superpowers" as well. As detailed in a new study published in the journal Science Translational Medicine, a team of scientists led by Columbia University professor of pediatric immunology, Dusan Bogunovic, has developed a new an