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Psilocybin prevents chemotherapy-induced nerve damage in mouse study

Researchers at MD Anderson Cancer Center found that two doses of psilocybin, the psychoactive compound in magic mushrooms, given before chemotherapy completely prevented mice from developing neuropathy, a painful nerve condition affecting up to 60% of patients on platinum-based cancer drugs. The findings, published in Science, suggest the compound protects sensory nerve endings from the energy depletion that chemotherapy drugs typically cause.

Large psilocybin brain-imaging study finds sharper, not chaotic, neural responses

A large neuroimaging study published in Nature gave 62 psychedelic-naive participants 19mg of oral psilocybin while they meditated, listened to music, or watched a movie, tracking activity across 332 brain regions with fMRI and EEG. Using AI to detect activity patterns tied to each task, researchers found that stronger psilocybin experiences produced clearer, more distinct neural signatures of what people were doing in the moment, even as boundaries between certain brain networks blurred.

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