Crypto billionaire Brian Armstrong is ready to invest in CRISPR baby tech

“I think the time is right for the defining company in the US to be built in this area,” Armstrong posted. The announcement from a deep-pocketed backer is a striking shift for a field considered taboo following the 2018 birth of the world’s first genetically edited children in China—a secretive experiment that led to international outrage and prison time for the lead scientist. According to Dieter Egli, a gene-editing scientist at Columbia University whose team has briefed Armstrong, his plans may be motivated in part by recent improvements in editing technology that have opened up a safer, more precise way to change the DNA of embryos. That technique, called base editing, can deftly change a single DNA letter. Earlier methods, on the other hand, actually cut the double helix, damaging it and causing whole genes to disappear. “We know much better now what to do,” says Egli. “It doesn’t mean the work is all done, but it’s a very different game now—entirely different.” Shoestring bud ... Read full article.