van der Ven, E. et al. Ethnoracial risk variation across the psychosis continuum in the US: a systematic review and meta-analysis. JAMA Psychiatry 81, 447–455 (2024).
International Schizophrenia, Consortium et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460, 748–752 (2009).
de Candia, T. R. et al. Additive genetic variation in schizophrenia risk is shared by populations of African and European descent. Am. J. Hum. Genet. 93, 463–470 (2013).
Lam, M. et al. Comparative genetic architectures of schizophrenia in East Asian and European populations. Nat. Genet. 51, 1670–1678 (2019).
Peterson, R. E. et al. Genome-wide association studies in ancestrally diverse populations: opportunities, methods, pitfalls, and recommendations. Cell 179, 589–603 (2019).
Gaziano, J. M. et al. Million Veteran Program: a mega-biobank to study genetic influences on health and disease. J. Clin. Epidemiol. 70, 214–223 (2016).
Ding, Y. et al. Polygenic scoring accuracy varies across the genetic ancestry continuum. Nature 618, 774–781 (2023).
Bigdeli, T. B. et al. Penetrance and pleiotropy of polygenic risk scores for schizophrenia, bipolar disorder, and depression among adults in the US Veterans Affairs health care system. JAMA Psychiatry 79, 1092–1101 (2022).
Harvey, P. D. et al. The genetics of functional disability in schizophrenia and bipolar illness: methods and initial results for VA cooperative study #572. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 165B, 381–389 (2014).
The All of Us Research Program Investigators. The “All of Us” Research Program. N. Engl. J. Med. 381, 668–676 (2019).
... continue reading