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Engineering tough blood clots for rapid haemostasis and enhanced regeneration

read original get Hemostatic Blood Clot Kit → more articles
Why This Matters

Advancements in engineering durable blood clots hold significant promise for improving rapid haemostasis and tissue regeneration, which can transform trauma care and wound healing. These innovations not only enhance the effectiveness of bleeding control but also support better healing outcomes, impacting both the medical industry and patient recovery experiences.

Key Takeaways

Guo, B., Dong, R., Liang, Y. & Li, M. Haemostatic materials for wound healing applications. Nat. Rev. Chem. 5, 773–791 (2021).

Weisel, J. W. Enigmas of blood clot elasticity. Science 320, 456–457 (2008).

Jiang, S., Liu, S., Lau, S. & Li, J. Hemostatic biomaterials to halt non-compressible hemorrhage. J. Mater. Chem. B 10, 7239–7259 (2022).

Bao, G. et al. Liquid-infused microstructured bioadhesives halt non-compressible hemorrhage. Nat. Commun. 13, 5035 (2022).

Yuk, H. et al. Rapid and coagulation-independent haemostatic sealing by a paste inspired by barnacle glue. Nat. Biomed. Eng. 5, 1131–1142 (2021).

Ovsianikov, A., Khademhosseini, A. & Mironov, V. The synergy of scaffold-based and scaffold-free tissue engineering strategies. Trends Biotechnol. 36, 348–357 (2018).

Lancaster, M. A. & Knoblich, J. A. Organogenesis in a dish: modeling development and disease using organoid technologies. Science 345, 1247125 (2014).

Brandenberg, N. et al. High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays. Nat. Biomed. Eng. 4, 863–874 (2020).

Stevens, A. J. et al. Programming multicellular assembly with synthetic cell adhesion molecules. Nature 614, 144–152 (2023).

Burdis, R. & Kelly, D. J. Biofabrication and bioprinting using cellular aggregates, microtissues and organoids for the engineering of musculoskeletal tissues. Acta Biomater. 126, 1–14 (2021).

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