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Tiny hubs of metabolic activity optimize nitrogen use in maize

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Why This Matters

This discovery sheds light on the spatial organization of nitrogen assimilation in maize cells, offering potential pathways to enhance nitrogen-use efficiency. Improving this efficiency can lead to more sustainable agriculture, reducing fertilizer waste and environmental impact while lowering costs for farmers. Such insights are crucial for advancing crop productivity and environmental conservation in the tech-driven agricultural sector.

Key Takeaways

Nitrogen is indispensable for plant growth and underpins global agricultural productivity. Yet modern crops use nitrogen from fertilizers strikingly inefficiently. In maize (Zea mays, also known as corn), typically less than one-third of applied nitrogen is converted into biomass, with the remainder lost to the environment, imposing economic costs and driving ecological damage1,2. Improving nitrogen-use efficiency is therefore a central goal in sustainable agriculture. Decades of research have led to the discovery of the enzymes responsible for nitrogen assimilation3,4 — the conversion of environmental nitrogen into useful organic substances such as amino acids — but not much is known about how this process is spatially organized in plant cells. Writing in Nature, Chen et al.5 reveal an unexpected mode of organization.

doi: https://doi.org/10.1038/d41586-026-01583-9

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Competing Interests The authors declare no competing interests.

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