New Myotis bat genome atlas links longevity genes and antiviral PKR evolution
Researchers sequenced high-quality genomes from several Myotis bat species, including M. lucifugus and M. velifer, using field-collected tissue and cell lines to capture full sex-chromosome data. They combined this genomic data with lab experiments on PKR antiviral proteins in engineered human cells to study how bats' immune genes evolved under viral pressure.
GoKawiil's interpretation of the reporting above, not reported fact.
Myotis bats are known for unusually long lifespans and unique tolerance to viruses, making them a key model for understanding aging and zoonotic disease resistance. Mapping how their antiviral genes like PKR evolved could inform research into human immune defenses and pandemic preparedness.
- New genome assemblies were built for multiple Myotis bat species using both wild-caught tissue and cultured cell lines.
- The study connects bat genome features to both extreme longevity and antiviral adaptation.
- Lab tests used engineered human cells to study bat PKR protein function against viral threats.
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Published there as: “Insights into longevity and virus-driven adaptation from <i>Myotis</i> bat genomes”
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