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Whole-genome ancestry of an Old Kingdom Egyptian

news.ycombinator.com Morez Jacobs 2025-08-16 14:24:46

Provenance and ethics The human remains were excavated from the Nuwayrat necropolis near Beni Hasan, Egypt. They were donated between 1902 and 1904 by the Egyptian Antiquities Service to the members of the Beni Hasan excavation committee and subsequently donated to the Institute of Archaeology, University of Liverpool and exported under the John Garstang export permit. The human remains were then donated to the World Museum (previously the Liverpool City Museum) in 1950. Sampling permit was gra

Topics: genomes nue001 ref supplementary using
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Scientists Playing God are Building Human DNA From the Ground Up

futurism.com Unknown 2025-08-23 08:45:21

Image by Getty / Futurism Studies Biological science has made such astonishing leaps in the last few decades, such as precise gene editing, that scientists are now tackling the next logical — yet inherently controversial — step: fabricating human DNA from the ground up. Details are a bit vague, but a team of scientists in the United Kingdom have embarked on a new project to construct what they describe in a statement as the "first synthetic human chromosome." The scientists hope that the five

Topics: genome genomes human project scientists
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Scientists Launch Wild New Project to Build a Human Genome From Scratch

gizmodo.com Natalia Mesa 2025-08-23 09:00:04

A team of UK-based researchers is going where no scientist has dared to go—writing artificial human DNA from scratch. They’re hoping the project will answer fundamental questions about the human genome and transform our understanding of health and disease. But the research topic is, for obvious reasons, controversial. Scientists have largely steered clear of trying to create full synthetic human genomes, wary of propelling us into a dystopian, Gattaca-esque future full of designer babies. Now,

Topics: create genome genomes human researchers
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AlphaGenome: AI for Better Understanding the Genome

news.ycombinator.com Unknown 2025-08-20 10:14:49

Science AlphaGenome: AI for better understanding the genome Share Copy link × Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function — now available via API. The genome is our cellular instruction manual. It’s the complete set of DNA which guides nearly every part of a living organism, from appearance and function to growth and reproduction. Small variations in a genome’s DNA sequence can alter a

Topics: alphagenome dna model sequence variants
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AlphaGenome: AI for better understanding the genome

news.ycombinator.com Unknown 2025-08-25 19:16:00

Science AlphaGenome: AI for better understanding the genome Share Copy link × Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function — now available via API. The genome is our cellular instruction manual. It’s the complete set of DNA which guides nearly every part of a living organism, from appearance and function to growth and reproduction. Small variations in a genome’s DNA sequence can alter a

Topics: alphagenome dna model sequence variants
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Google DeepMind Releases AlphaGenome

news.ycombinator.com Unknown 2025-08-26 20:16:00

Science AlphaGenome: AI for better understanding the genome Share Copy link × Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function — now available via API. The genome is our cellular instruction manual. It’s the complete set of DNA which guides nearly every part of a living organism, from appearance and function to growth and reproduction. Small variations in a genome’s DNA sequence can alter a

Topics: alphagenome dna model sequence variants
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Google’s new AI will help researchers understand how our genes work

technologyreview.com Antonio Regalado 2025-08-29 14:00:00

“We haven’t designed or validated AlphaGenome for personal genome prediction, a known challenge for AI models,” Google said in a statement. Underlying the AI system is the so-called transformer architecture invented at Google that also powers large language models like GPT-4. This one was trained on troves of experimental data produced by public scientific projects. Lareau says the system will not broadly change how his lab works day to day but could permit new types of research. For instance,

Topics: ai alphagenome google new says
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Researchers get viable mice by editing DNA from two sperm

arstechnica.com Unknown 2025-09-02 02:34:11

For many species, producing an embryo is a bit of a contest between males and females. Males want as many offspring as possible, and want the females to devote as many resources as possible to each of them. Females are better at keeping their options open and distributing resources in a way to maximize the number of offspring they can produce over the course of their lives. In mammals, this plays out through the chemical modification of DNA, a process called imprinting. Males imprint their DNA

Topics: dna eggs females genome offspring
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