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Biotech Startup Claims It’s Getting Closer to ‘Resurrecting’ the Extinct Dodo

A version of the dodo bird (Raphus cucullatus) could make a return someday soon. Colossal Biosciences announced this week several milestones in its quest to bring the extinct species back to life. On Wednesday, the Dallas-based company reported that its researchers at the Avian Genetics Group have successfully grown pigeon primordial germ cells (PGCs) in the lab, a scientific first. They also bred gene-edited chickens intended to serve as potential surrogates for the dodo and other ancient bird

Scientists Gather to Confront the Doomsday Risks of ‘Mirror Life’

The prospect of creating “mirror life”—synthetic cells made from molecules that are mirror images of those found in nature—remains completely hypothetical. Still, the potential consequences are so dire that experts from around the world are gathering to discuss how to prevent the worst-case scenario. This week, scientists, engineers, policymakers, and other stakeholders will convene in Manchester, U.K., for Engineering and Safeguarding Synthetic Life 2025. This annual international conference e

Harvard's new free AI tool could help treat Parkinson's, Alzheimer's, and even cancer

Nemes Laszlo/Science Photo Library/Getty Images Follow ZDNET: Add us as a preferred source on Google. ZDNET's key takeaways Harvard researchers designed a new AI model, PDGrapher. It can identify treatments to restore diseased cells to health. This could have larger impacts on drug discovery. While AI's most common use cases involve helping people with their everyday tasks, it can also go far beyond that, even helping make medical breakthroughs. Also: Can AI outdiagnose doctors? Microsoft

When Astronauts Enter Space, a "Dark Genome" Activates in Their DNA

Image by Getty / NASA / Futurism Studies Researchers have found that human stem cells are constantly under stress in the microgravity of space — activating hidden, ancient sections of DNA called the "dark genome." In a study published in the journal Cell Stem Cell last week, a team of researchers led by Sanford Stem Cell Institute director Catriona Jamieson used a cellphone-sized device on board the International Space Station to watch how stem cells behave in space for the first time. They f

Gene-edited pancreatic cells transplanted into a patient with type 1 diabetes

Crispr gene-editing technology has demonstrated its revolutionary potential in recent years: It has been used to treat rare diseases, to adapt crops to withstand the extremes of climate change, or even to change the color of a spider’s web. But the greatest hope is that this technology will help find a cure for a global disease, such as diabetes. A new study points in that direction. For the first time, researchers succeeded in implanting Crispr-edited pancreatic cells in a man with type 1 diab

CRISPR offers new hope for treating diabetes

Crispr gene-editing technology has demonstrated its revolutionary potential in recent years: It has been used to treat rare diseases, to adapt crops to withstand the extremes of climate change, or even to change the color of a spider’s web. But the greatest hope is that this technology will help find a cure for a global disease, such as diabetes. A new study points in that direction. For the first time, researchers succeeded in implanting Crispr-edited pancreatic cells in a man with type 1 diab

CRISPR Offers New Hope for Treating Diabetes

Crispr gene-editing technology has demonstrated its revolutionary potential in recent years: It has been used to treat rare diseases, to adapt crops to withstand the extremes of climate change, or even to change the color of a spider’s web. But the greatest hope is that this technology will help find a cure for a global disease, such as diabetes. A new study points in that direction. For the first time, researchers succeeded in implanting Crispr-edited pancreatic cells in a man with type 1 diab

Crispr Offers New Hope for Treating Diabetes

Crispr gene-editing technology has demonstrated its revolutionary potential in recent years: It has been used to treat rare diseases, to adapt crops to withstand the extremes of climate change, or even to change the color of a spider’s web. But the greatest hope is that this technology will help find a cure for a global disease, such as diabetes. A new study points in that direction. For the first time, researchers succeeded in implanting Crispr-edited pancreatic cells in a man with type 1 diab

Researchers Create 3D-Printed Artificial Skin That Allows Blood Circulation

When treating severe burns and trauma, skin regeneration can be a matter of life or death. Extensive burns are usually treated by transplanting a thin layer of epidermis, the top layer of skin, from elsewhere on the body. However, this method not only leaves large scars, it also does not restore the skin to its original functional state. Unless the dermis, the layer below the epidermis, which contains blood vessels and nerves, is regenerated, it cannot be considered normal living skin. Now, wor

Immunotherapy drug clinical trial results: half of tumors shrink or disappear

Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise—and induced great disappointment. While effective at activating the immune system to kill cancer cells in animal models, the drugs had limited impact on patients in clinical trials and caused dangerously systemic inflammatory responses, low platelet counts, and liver toxicity, among other adverse reactions—even at a low dose. But in 2018, the lab of Rockefeller University’s Jeffrey V. Ravetch

Immunotherapy drug eliminates aggressive cancers in clinical trial

Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise—and induced great disappointment. While effective at activating the immune system to kill cancer cells in animal models, the drugs had limited impact on patients in clinical trials and caused dangerously systemic inflammatory responses, low platelet counts, and liver toxicity, among other adverse reactions—even at a low dose. But in 2018, the lab of Rockefeller University’s Jeffrey V. Ravetch

Human stem cells age more rapidly in space, study finds

While scientists are still working to understand the effects an extended trip to space can have on the human body, research in recent years has suggested that astronauts may experience some pretty dramatic changes on both the physiological and psychological levels. In the latest study led by a team at University of California San Diego, researchers found signs of accelerated aging in human stem cells that spent roughly a month in space. The research focused on hematopoietic stem and progenitor

Going to Space Could Make Your Cells Age Faster

Spaceflight pushes the human body to its limits, exposing astronauts to microgravity, high levels of radiation, and extended periods of isolation. These stressors affect their health in various ways, many of which scientists are still working to fully understand. But if we are ever to boldly go where no human has gone before, we need to know all the risks before we take the leap. And now new research published Thursday, September 4 in the journal Cell Stem Cell offers clues to another facet of

Scientists just found a protein that reverses brain aging

Aging is particularly harsh on the hippocampus -- the brain region responsible for learning and memory. Now, researchers at UC San Francisco have identified a protein that's at the center of this decline. They looked at how the genes and proteins in the hippocampus changed over time in mice and found just one that differed between old and young animals. It's called FTL1. Old mice had more FTL1, as well as fewer connections between brain cells in the hippocampus and diminished cognitive abilit

Topics: cells ftl1 mice old phd

The Weight of a Cell

Ella Watkins-Dulaney Microbes are so small that tens of thousands could fit in the space of the period at the end of this sentence. And yet, for two of the most widely studied kinds — S. cerevisiae and E. coli — we know their weight with remarkable precision: A single yeast cell weighs about 100 picograms and a single E. coli bacterium weighs about one picogram, or 60 million times less than a grain of sand. At first blush, measuring the weight of a single cell seems an impossible task. How ca

Representing Python notebooks as dataflow graphs

This blog is adapted from our talk at PyCon 2025. marimo is free and open source, available on GitHub. For a free online experience with link sharing, try molab. marimo is a new kind of open-source Python notebook. While traditional notebooks are just REPLs, marimo notebooks are Python programs represented as dataflow graphs. This intermediate representation lets marimo blend the best parts of interactive computing with the reproducibility and reusability of Python software: every marimo notebo

New Gel Could Heal Stubborn Diabetic Wounds in Under 2 Weeks

For people with diabetes, high blood sugar can damage blood vessels and nerves, leading to chronic wounds that stay open for months. But a new gel-based treatment could massively speed up the healing process for people with diabetes, allowing wounds to close in just days, according to a new study. The new treatment targets thrombospondin-1 (TSP-1), a protein that inhibits the growth of new blood vessels, a crucial step in the healing process. Targeting this protein increased new blood vessel fo

Diabetic Man With Gene-Edited Cells Produces His Own Insulin—No Transplant Drugs Required

A new case study offers a tantalizing glimpse into the potential future of transplantation medicine. A man with type 1 diabetes is now able to make his own insulin thanks to a transplant of gene-edited pancreatic cells—a transplant that hasn’t required the typical drugs used to avoid rejection. Scientists in Sweden and the U.S. conducted the research, published this week in the New England Journal of Medicine. The 42-year-old man with long-standing diabetes was given donated islet cells that we

Scientists Find Evidence That Aging Is Contagious

Image by Getty / Futurism Studies Eventually, aging comes for us all — but new evidence suggests that in key ways, it may be a contagious condition. In a provocative new study published in the journal Metabolism, scientists from South Korea and the United States found, while doing studies on human cells and with mice, that injecting the DNA messenger protein HMGB1 from an older individual can result in processes that very much look like aging. Though it typically lives within cell nuclei and

How to Scale Proteomics

A cell is a vibrating bag of molecules, densely packed with DNA, proteins, RNAs, and lipids. The ratios of these molecules are not balanced, though. A typical HeLa cell, widely used as a model to study cancer in the laboratory, has about 20 times more protein than DNA by mass. Such imbalances are pervasive across the tree of life, but proteins are always the heaviest and most diverse group of molecules within a cell. A single human cell encodes more than 20,000 proteins, each built from 20 stan

Fire hazard of WHY2025 badge due to 18650 Li-Ion cells

This document was originally posted in two places: A response was published by IFCAT: This page is also reachable via WHY18650.org WHY2025 badge fire hazard advisory The WHY2025 badge is a fire hazard when used with unprotected cells. Unprotected cells themselves are intrinsically unsafe and require additional safety measures which are not provided by the badge. In fact, the badge makes it worse. Background information Visitors of WHY2025 can get a badge, a fun electronic gadget that is a

Tesla picks LGES, not CATL, for $4.3 billion storage battery deal

Tesla has a new battery cell supplier. Although the automaker is vertically integrated to a degree not seen in the automotive industry for decades, when it comes to battery cells it’s mostly dependent upon suppliers. Panasonic cells can be found in many Teslas, with the cheaper, sturdier lithium iron phosphate (LFP) battery cells being supplied by CATL. Now Tesla has a new source of LFP cells thanks to a deal just signed with LG Energy Solutions. According to The Korea Economic Daily, the contr

Optimi-Zi(n)g Sudoku-Solving

Optimi-Zi(n)g Sudoku-Solving 26 July 2025 , in Olivier's log One of the first program that I wrote in Zig (in September 2023) was a Sudoku-Solver, implementing the dancing-links (DLX) algorithm. I decided to revisit this program recently to experiment with benchmarking and try to increase its speed. Dancing-Links (DLX) algorithm applied to sudoku The Dancing-Links algorithm is an efficient backtracking algorithm to solve "exact-cover" problems, by using a matrix of 0 and 1s. Dancing Links o

Florida Is Now a Haven for Unproven Stem-Cell Treatments

Florida is the latest state to sidestep the authority of the Food and Drug Administration by allowing patients to access certain stem-cell treatments that have not been rigorously evaluated and approved. Under a new law that went into effect July 1, doctors in Florida can administer unapproved stem-cell therapies for wound care, pain management, or orthopedic purposes. The law comes amid growing support for medical freedom in the United States, an idea espoused by Health and Human Services secr

Newly Discovered Gut ‘Sense’ Could Change How We Think About Hunger and Health

There really is something to the concept of having a gut feeling. New research out today suggests our bodies can directly sense and communicate with the many bacteria lining our digestive tract. Scientists at Duke University led the study, published Wednesday in Nature. They found that nerve cells can respond in real time to bacterial signals from the gut—including signals that tell us to curb our appetite. The findings suggest the relationship we have with our microbial neighbors is even more

This X-ray view may shed some light on Anker’s recalled power banks

Edgar Cervantes / Android Authority TL;DR A firm specializing in X-ray CT scans has investigated the recently recalled Anker power banks. The scans show there are a few differences between the recalled models and the ones not recalled. Back in June, Anker recalled over 1 million of its PowerCore 10000 power banks (model A1263). Although the company didn’t go into details about what was wrong with the device, it did mention that units sold between 2016 and 2022 pose a potential fire safety ris

Super-resolution microscopes reveal new details of cells and disease

Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells in human tissues, and observe “animalcules” — bacteria and protists — in the water of a lake. Increasingly powerful light microscopes followed, revealing cell organelles like the nucleus and energy-producing mitochondria. But by 1873, scientists realized there was a limit to the level of detail. W

Erythritol linked to brain cell damage and stroke risk

From low-carb ice cream to keto protein bars to "sugar-free" soda, the decades-old sweetener erythritol is everywhere. But new University of Colorado Boulder research shows the popular sugar substitute and specialty food additive comes with serious downsides, impacting brain cells in numerous ways that can boost risk of stroke. The study was published in the Journal of Applied Physiology. "Our study adds to the evidence suggesting that non-nutritive sweeteners that have generally been purport

Popular Sugar Substitute Marketed to Diabetics Linked to Stroke, Heart Attack, Brain Cell Damage

Image by Getty Images Studies A widely-used sugar substitute found in products marketed to people with diabetes may involve more risks than rewards. In a new study published in the Journal of Applied Physiology, researchers from the University of Colorado Boulder found that erythritol — an organic compound used for so-called "stevia" products sold by the brands Wholesome, Truvia, and Splenda — can harm brain cells and increase the risk of stroke and heart attack. Created during the corn ferme

What's going on with gene therapies?

Tree of Hope, Remain Strong (1946) by Frida Kahlo First attempts in a new field of medicine rarely go according to plan. On September 14, 1990, Dr. William French Anderson and his team at the National Institute of Health (NIH) performed the first official gene therapy trial. The patient, a 4-year-old Ashanti deSilva, suffered from a rare genetic disease called adenosine deaminase (ADA) deficiency, a form of severe combined immune deficiency (SCID). Children with ADA-SCID rarely make it to adult