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WIRED Health Recap: Cancer Vaccines, Crispr Breakthroughs, and More

At the WIRED Health summit in Boston on September 9, we hosted some of the leading experts in Crispr, whole-genome sequencing, vaccines, and more for a series of eye-opening conversations and keynotes. If you weren’t able to join us in person, no worries; you can watch them all right here. From 2025 Breakthrough Prize winner David Liu to Moderna CEO Stepháne Bancel, WIRED Health speakers gave deep insights into what’s next for gene-editing, cancer treatment, and a host of other cutting-edge top

WIRED Health Recap: Cancer Vaccines, CRISPR Breakthroughs, and More

At the WIRED Health summit in Boston on September 9, we hosted some of the leading experts in CRISPR, whole-genome sequencing, vaccines, and more for a series of eye-opening conversations and keynotes. If you weren’t able to join us in person, no worries; you can watch them all right here. From 2025 Breakthrough Prize winner David Liu to Moderna CEO Stepháne Bancel, WIRED Health speakers gave deep insights into what’s next for gene-editing, cancer treatment, and a host of other cutting-edge top

Immunotherapy drug clinical trial results: half of tumors shrink or disappear

Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise—and induced great disappointment. While effective at activating the immune system to kill cancer cells in animal models, the drugs had limited impact on patients in clinical trials and caused dangerously systemic inflammatory responses, low platelet counts, and liver toxicity, among other adverse reactions—even at a low dose. But in 2018, the lab of Rockefeller University’s Jeffrey V. Ravetch

Immunotherapy drug eliminates aggressive cancers in clinical trial

Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise—and induced great disappointment. While effective at activating the immune system to kill cancer cells in animal models, the drugs had limited impact on patients in clinical trials and caused dangerously systemic inflammatory responses, low platelet counts, and liver toxicity, among other adverse reactions—even at a low dose. But in 2018, the lab of Rockefeller University’s Jeffrey V. Ravetch

Nobel laureate David Baltimore dead at 87

Nobel Prize-winning molecular biologist and former Caltech president David Baltimore—who found himself at the center of controversial allegations of fraud against a co-author—has died at 87 from cancer complications. He shared the 1975 Nobel Prize in Physiology for his work upending the then-consensus that cellular information flowed only in one direction. Baltimore is survived by his wife of 57 years, biologist Alice Huang, as well as a daughter and granddaughter. "David Baltimore's contributi

Join Relay in supporting St. Jude Children’s Research Hospital

Once again, our friends over at Relay have launched their annual campaign to raise money for St. Jude Children’s Research Hospital. The Relay community has raised over $4 million for St. Jude since 2019. I’ve set up a 9to5Mac fundraising page for St. Jude through the Relay campaign. You can visit that page to make your donation and earn some rewards in the process. St. Jude is a decades-old children’s research hospital based in Tennessee that aims to find new treatments and cures for childhood

People Who Don't Smoke Are Getting Lung Cancer in Scary Numbers

Image by Getty / Futurism Cancer It's no secret that our efforts to save the planet from the excesses of global trade are failing spectacularly. Our bodies are riddled with manmade compounds, cities are routinely enveloped by massive clouds of noxious smoke, and glaciers are melting faster than ever before. Indeed, in 2025, not even the remote ice shelves of Antarctica are safe from humanity's garbage. At the same time as the Earth struggles to hold the weight of all our garbage, a concerning

Researchers Find Strange Link Between Marathon Running and Cancer

Some of the most physically fit people in the world may have a unique health risk. New research uncovers a possible link between marathon running and colorectal cancer. Oncologists at the Inova Schar Cancer Institute in Virginia conducted the study, which examined the colons of relatively young people who had run several long-distance races. They found these runners had a much higher rate of having potentially dangerous adenomas (a type of polyp) than would be expected for their age. Though the

The First At-Home Cervical Cancer Screening Wand: Cost, Insurance Coverage and How It Works

Many people dread going into the doctor's office for a Pap smear or HPV test, but that's no longer the only cervical cancer screening option. Now, we have the Teal Wand, the first and only at-home vaginal sample self-collection device for cervical cancer screening in the US. It allows people with a cervix to easily screen themselves for the highly preventable cancer from the comfort of their home. After receiving FDA approval in May, the Teal Wand is now available in California. By 2027, it sho

What Seemed Like a Pregnancy Was Actually Something Far More Dangerous

A woman’s supposed pregnancy turned out to be something much stranger. In a recent report from her doctors, they detail how the woman had developed an incredibly rare form of ovarian cancer that mimicked the symptoms of pregnancy, even causing a positive pregnancy test. Doctors in India described the case of mistaken identity earlier this July in the journal Oncoscience. After first suspecting the woman had an ectopic pregnancy, the doctors instead discovered a large and rare type of tumor in h

A Common Virus Causes Cancer, but Most Americans Are Clueless About It

The human papillomavirus (HPV) is a major source of cancer that’s now almost entirely preventable through vaccination. But sobering research out today shows that Americans are largely in the dark about HPV and its many health risks, much less the HPV vaccine. Researchers at the Medical University of South Carolina conducted the study, which examined nationally representative survey data. A third of Americans don’t know that the virus exists, they found, while most who do know are still unaware

The First At-Home Cervical Cancer Screening Wand: Does It Replace Uncomfortable Pap Smears?

Cervical cancer is highly preventable with routine screening, but it isn't always a pleasant experience. That's why women's health company Teal Health created the Teal Wand, the first and only at-home vaginal sample self-collection device for cervical cancer screening in the US. Now, people with a cervix can conveniently screen themselves from the comfort and privacy of their home. The Teal Wand received FDA approval in May and is currently available in California. It should be accessible acros

New treatment eliminates bladder cancer in 82% of patients

TAR-200 is a miniature, pretzel-shaped drug-device duo containing a chemotherapy drug, gemcitabine, which is inserted into the bladder through a catheter and releases the drug for three weeks per treatment cycle. How the drug delivery system works TAR-200 is a miniature, pretzel-shaped drug-device duo containing a chemotherapy drug, gemcitabine, which is inserted into the bladder through a catheter. Once inside the bladder, the TAR-200 slowly and consistently releases the gemcitabine into the

The First At-Home Cervical Cancer Screening Wand Is Now Available. This Is How It Works and Who Can Use It

If you've ever had a Pap smear, you know how uncomfortable a cervical cancer screening can be, especially from inside a cold, clinical doctor's office. Cervical cancer is highly preventable with routine screening. To provide people with a cervix a comfortable and private screening option, women's health company Teal Health developed the Teal Wand, the first and only at-home vaginal sample self-collection device for cervical cancer screening in the US. Following its FDA approval in May, the Tea

Teen Influencer Stranded in Antarctica After Controversial Plane Landing

An American teenager is currently stuck in Antarctica after illegally landing his single-engine airplane in Chilean territory. 19-year-old Ethan Guo, who was in the midst of navigating a trip around the world when he landed at the world’s southernmost pole, has been stuck in the icy region since June, according to the Associated Press. Upon landing, local officials charged Guo with providing them with “false flight plan information” and landing without authorization. Since then, he has been sta

Experimental ‘Off-the-Shelf’ Cancer Vaccine Is Already Prolonging Lives, Study Suggests

An experimental “off-the-shelf” vaccine for recurring pancreatic and colorectal cancer is showing great promise so far. Early results show that the vaccine appears to be safe and is potentially prolonging people’s lives. Researchers at the University of California, Los Angeles, the Memorial Sloan Kettering Cancer Center in New York, and elsewhere are developing the vaccine, called ELI-002. In Phase I trial data released this week, people who received ELI-002 often developed an immune response t

The First At-Home Cervical Cancer Screening Wand Is Now Available

If you've ever had a Pap smear, you know how uncomfortable a cervical cancer screening can be, especially from inside a cold, clinical doctor's office. Cervical cancer is highly preventable with routine screening. To provide people with a cervix a comfortable and private screening option, women's health company Teal Health developed the Teal Wand, the first and only at-home vaginal sample self-collection device for cervical cancer screening in the US. Following its FDA approval in May, the Tea

Scientists are growing tumors in space to study how to personalize cancer treatment

Forward-looking: Although precision medicine has advanced rapidly in recent years, many cancer patients still undergo standard treatments that may not work for everyone. Research underway on the International Space Station offers a glimpse of future care, where doctors map out each course of therapy using a detailed simulation of the patient's cancer. In a laboratory more than 249 miles above Earth, a new generation of cancer research is unfolding. A biotech startup is harnessing the microgravi

No, the Sun Isn't Safer Than Tanning Beds. Plus, 17 Other Health Myths We're Busting

Cracking your knuckles will cause arthritis. Eggs raise your cholesterol levels. Coffee stunts your growth. For decades, myths like these have influenced consumer decisions, originating from obscure studies or the opinion of a health "influencer". Science has debunked much of this conventional wisdom that percolates as fact. Here are 18 common health myths that everyone needs to stop believing right now. Myth: Exercising at night ruins your sleep Feel free to work out at night if that's your j

Rare Bone-Eating Cancer Replaced Man’s Finger and Toe

A 55-year-old man’s swollen toes and fingers turned out to have a much stranger explanation than expected. In a recent case report, the man’s doctors detailed how some of his bones were “completely replaced” by metastatic tumors. Doctors in Australia described the case earlier this month in the New England Journal of Medicine. The man visited the hospital after weeks of having pain and swelling in one finger and one toe. They soon discovered the symptoms were an unusual complication of the man’

Many lung cancers are now in nonsmokers

Annie Chen first noticed she was unusually short of breath in 2017, while running to catch the bus home to New Jersey from her job in Manhattan. She told her primary care doctor, thinking of her father, who died of lung cancer at 71. But her doctor told her not to worry — her father was a heavy smoker, and Ms. Chen had never smoked. She continued to have difficulty breathing, but it wasn’t until two years later that a doctor ordered an X-ray, and Ms. Chen was diagnosed with Stage 4 lung cancer.

Many Lung Cancers Are Now in Nonsmokers. Scientists Want to Know Why

Annie Chen first noticed she was unusually short of breath in 2017, while running to catch the bus home to New Jersey from her job in Manhattan. She told her primary care doctor, thinking of her father, who died of lung cancer at 71. But her doctor told her not to worry — her father was a heavy smoker, and Ms. Chen had never smoked. She continued to have difficulty breathing, but it wasn’t until two years later that a doctor ordered an X-ray, and Ms. Chen was diagnosed with Stage 4 lung cancer.

Cancer DNA is detectable in blood years before diagnosis

Cancer’s genetic fingerprints may lurk in people’s blood long before they find out about the disease. It’s possible to spot tumor DNA more than three years before a person is diagnosed with cancer, researchers report May 22 in Cancer Discovery. “We were shocked that we could find DNA,” says Yuxuan Wang, an oncologist and cancer researcher at Johns Hopkins University School of Medicine. The findings suggest that hunting for these telltale traces using highly sensitive and accurate technology co

Gastrointestinal Cancers Are Surging Among Young Americans, and No One Is Quite Sure Why

Young people appear to be increasingly vulnerable to gastrointestinal cancers, but researchers aren’t entirely sure what is driving the surge in disease. In a new study out this week, scientists led by the Dana-Farber Cancer Institute found that rates of early-onset GI cancers—those occurring in people younger than 50—are rising more rapidly than other types of cancer. In particular, colorectal cancer cases have significantly increased, while rates of other forms of the disease, like stomach ca

What’s on offer at a luxury Bay Area longevity clinic

Human Longevity, a medical clinic in South San Francisco’s biotech corridor, feels more like a spa than a doctor’s office. The floors of the 8,000-square-foot space are sleek and white, the walls bamboo with moss accents. Visitors are referred to as clients, not patients, as they are ushered into private rooms equipped with Wi-Fi, snacks, full bathrooms with showers, and cameras for Zoom meetings — a feature meant to accommodate executives who fly in for the day for multi-hour batteries of test

Colon Cancer Explained: Warning Signs, Risk Factors and Prevention

Colon cancer is a leading cause of cancer-related deaths worldwide, and it's important to be aware of the symptoms as well as what you can do to prevent this deadly illness. Colorectal or colon cancer (not to be confused with stomach or gastric cancer) has become a hot topic in recent years with news of celebrities -- such as Chadwick Boseman and Kirstie Alley-- passing away after battling the disease. In 2025, the American Cancer Society estimates that there will be about 107,320 new cases of c

No. Eggs Won't Impact Your Cholesterol and 17 Other Health Myths You Can Stop Believing

Cracking your knuckles will cause arthritis. Eggs impact your cholesterol levels. Coffee stunts your growth. For decades, health myths like these have influenced consumer decisions, originating from obscure studies or the opinion of a then-influential doctor. Science has debunked much of this conventional wisdom that percolates as fact. Here are 18 of the most common health myths that everyone needs to stop believing right now. Myth: Exercising at night ruins your sleep Feel free to work out a

Air pollution may contribute to development of lung cancer in never-smokers

Now, a study published on July 2 in Nature has uncovered compelling genomic evidence that points to air pollution—and other environmental exposures—as a potential major factor behind this growing public health concern. The study was jointly led by researchers at the University of California San Diego and the National Cancer Institute (NCI), part of the National Institutes of Health (NIH). “We’re seeing this problematic trend that never-smokers are increasingly getting lung cancer, but we haven’

Air Pollution May Contribute to Development of Lung Cancer in Never-Smokers

Now, a study published on July 2 in Nature has uncovered compelling genomic evidence that points to air pollution—and other environmental exposures—as a potential major factor behind this growing public health concern. The study was jointly led by researchers at the University of California San Diego and the National Cancer Institute (NCI), part of the National Institutes of Health (NIH). “We’re seeing this problematic trend that never-smokers are increasingly getting lung cancer, but we haven’

Notorious Fungus Blamed for ‘Mummy’s Curse’ Is Now a Promising Cancer Treatment

In the 1920s, a number of workers on the excavation team that uncovered King Tutankhamun’s tomb met untimely deaths. Five decades later, 10 out of 12 scientists died after entering the tomb of the 15th-century Polish King Casimir IV. In both cases, researchers suggested that fungal spores could have played a role in the mysterious deaths, specifically identifying the fungus Aspergillus flavus within the Polish burial. A. flavus is now making a comeback, but not as a reawakened killer from ancie