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Evidence Grows That Tripping on Shrooms Might Increase Your Lifespan

Image by JASON CONNOLLY/AFP via Getty Images Studies In a new study, scientists have uncovered evidence that magic mushrooms just might be an effective anti-aging treatment. Published in the Nature Partnering Journal Aging, a new paper by researchers at Emory and Baylor's medical schools suggests that psilocybin, the active compound in psychedelic mushrooms — there are a range of species that produce it, but the best known is probably Pisolocybe cubensis — might extend the lifespans of both mi

Scientists Gene Hack Mice So Their Livers Produce Their Own Ozempic-Like Drug

Image by Remi Benali/Getty Images Rx/Medicines Scientists have gene-hacked mice to produce their own Ozempic-like drugs — possibly, and provocatively, perhaps paving a path for humans to do so themselves one day. In a new study published in the journal Communications Medicine, researchers from Japan's University of Osaka successfully gene-edited mice livers to produce exenatide, a first-generation diabetes drug and predecessor to now-trendy jabs like Ozempic and Mounjaro. Using lab mice that

Scientists Succeed in Reversing Parkinson’s Symptoms in Mice

Cases of Parkinson’s disease have doubled in the last 25 years, according to figures from the World Health Organization. For decades, the scientists have investigated what triggers this disorder to mitigate its symptoms and anticipate its onset. Now, a series of experimental therapies are laying the groundwork for potentially reversing the condition, which affects nearly 10 million people worldwide and can generate costs of approximately $10,000 per patient per year, when considering direct and

These Genetically Modified Mice Make Their Own ‘Ozempic’

The popularity of Ozempic and Wegovy as diabetes and weight loss medications has skyrocketed. But how far would people go to avoid one of their major drawbacks—the need for weekly injections? A study out today shows it’s possible to genetically modify mice to make their own Ozempic-like drugs. Scientists in Japan led the research, which involved gene-editing mice’s livers to produce an internal supply of exenatide, a first-generation GLP-1 drug. The edited mice were able to sustain levels of th

Changing one gene can restore some tissue regeneration to mice

Regeneration is a trick many animals, including lizards, starfish, and octopuses, have mastered. Axolotls, a salamander species originating in Mexico, can regrow pretty much everything from severed limbs, through eyes and parts of brain, to the spinal cord. Mammals, though, have mostly lost this ability somewhere along their evolutionary path. Regeneration persisted, in a limited number of tissues, in just a few mammalian species like rabbits or goats. “We were trying to learn how certain anima