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Psilocybin decreases depression and anxiety in cancer patients (2016)

Participants with a potentially life-threatening cancer diagnosis and a DSM-IV diagnosis that included anxiety and/or mood symptoms were recruited through flyers, internet, and physician referral. Of 566 individuals who were screened by telephone, 56 were randomized. Figure 1 shows a CONSORT flow diagram. Table 1 shows demographics for the 51 participants who completed at least one session. The two randomized groups did not significantly differ demographically. All 51 participants had a potentia

Psilocybin produces substantial sustained decreases in depression and anxiety

Participants with a potentially life-threatening cancer diagnosis and a DSM-IV diagnosis that included anxiety and/or mood symptoms were recruited through flyers, internet, and physician referral. Of 566 individuals who were screened by telephone, 56 were randomized. Figure 1 shows a CONSORT flow diagram. Table 1 shows demographics for the 51 participants who completed at least one session. The two randomized groups did not significantly differ demographically. All 51 participants had a potentia

Show HN: We made our own inference engine for Apple Silicon

uzu A high-performance inference engine for AI models on Apple Silicon. Key features: Simple, high-level API Hybrid architecture, where layers can be computed as GPU kernels or via MPSGraph (a low-level API beneath CoreML with ANE access) Unified model configurations, making it easy to add support for new models Traceable computations to ensure correctness against the source-of-truth implementation Utilizes unified memory on Apple devices Quick Start First, add the uzu dependency to your

Topics: let model run session uzu

Show HN: Cogency – Cognitive Architecture for AI Agents

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The votes are in: TechCrunch Disrupt 2025 Audience Choice winners revealed for roundtables and breakouts

You voted — they made it onto the TechCrunch Disrupt 2025 agenda! After reviewing hundreds of standout Call for Content submissions and opening the vote to the TechCrunch audience, we’ve locked in the top five roundtables and top five breakout sessions. Without further ado, meet the exceptional tech voices — and the sessions they’ll lead — that will shape the conversation at Disrupt 2025, taking place October 27–29 at San Francisco’s Moscone West. Visit the agenda page for full session and spe

Jack Dorsey’s latest app tracks sun exposure

Twitter co-founder Jack Dorsey is on an app-building spree. After releasing a Bluetooth-based messaging app called Bitchat earlier this month, this weekend Dorsey revealed another app called Sun Day that ostensibly helps users track UV exposure and Vitamin D intake. The new app is available via TestFlight on iOS, and its code is on GitHub for anyone to clone. track your (vitamin) D a Sun Day app for Sunday.https://t.co/KKsq3LkLEj — jack (@jack) July 13, 2025 Like other developers, Dorsey i

Show HN: BinaryRPC – Lightweight WebSocket-based RPC framework in modern C++

BinaryRPC 🧭 Motivation While working at my company, I had previously developed a WebSocket server prototype in Java. However, over time, we started to experience performance issues. This led me to turn to C++, a language that offers more speed and low-level system control. Through my research, I discovered that uWebSockets was one of the best options in terms of performance, so I began developing with this library. However, since uWebSockets is a very "core" library, I had to handle many deta

Top DNS domains seen on the Quad9 recursive resolver array each day

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Show HN: CXXStateTree – A modern C++ library for hierarchical state machines

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A Emoji Reverse Polish Notation Calculator Written in COBOL

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Show HN: A rain Pomodoro with brown noise, ASMR, and Middle Eastern music

Can I use Rain Pomodoro timer for studying and work? Absolutely! Rain Pomodoro is perfect for both studying and work. The pomodoro technique's 25-minute focus sessions are ideal for maintaining concentration during study sessions, while the variety of background sounds (rain, brown noise, ASMR, desert ambience) allows you to customize your environment based on the type of work you're doing. The visual rain effects also help reduce eye strain during long computer sessions.

I Ported SAP to a 1976 CPU. It Wasn't That Slow

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A Rust-TypeScript integration

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Escher's art and computer science

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Mo Jomaa breaks down IPO prep for founders on the Scale Stage at TechCrunch All Stage

An IPO may not be on your near-term roadmap, but the best founders start planning for it long before the bankers show up. At TechCrunch All Stage on July 15 at Boston’s SoWa Power Station, Mo Jomaa, partner at CapitalG (Alphabet’s independent growth fund), will lead a session titled “What to Think About Now If You Want to IPO Someday” on the Scale Stage. In this session, Jomaa will walk founders through what it really takes to build toward a public debut, with lessons drawn from years investin

Kristen Craft brings fresh fundraising strategy to the Foundation Stage at TechCrunch All Stage

Raising in 2025 doesn’t look anything like it did in 2021 — and that’s exactly the point. At TechCrunch All Stage on July 15 at Boston’s SoWa Power Station, Kristen Craft, Head of Business Development at Fidelity Private Shares, will lead a roundtable session titled “It’s Not 2021 Anymore. Navigating the 2025 VC Landscape,” happening on the Foundation Stage. In this conversation, Craft will guide founders through the new norms of venture capital. From shifting investor expectations to sharper

Show HN: TokenDagger – A tokenizer faster than OpenAI's Tiktoken

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Citrix Bleed 2 flaw now believed to be exploited in attacks

A critical NetScaler ADC and Gateway vulnerability dubbed "Citrix Bleed 2" (CVE-2025-5777) is now likely exploited in attacks, according to cybersecurity firm ReliaQuest, seeing an increase in suspicious sessions on Citrix devices. Citrix Bleed 2, named by cybersecurity researcher Kevin Beaumont due to its similarity to the original Citrix Bleed (CVE-2023-4966), is an out-of-bounds memory read vulnerability that allows unauthenticated attackers to access portions of memory that should typically

David H. Rosmarin brings a founder-focused approach to anxiety at TechCrunch All Stage

Startups demand constant decision-making, pressure-filled pivots, and bring big emotional swings. It’s no wonder anxiety shows up at every stage. But what if it didn’t have to be a liability? At TechCrunch All Stage 2025 on July 15 at Boston’s SoWa Power Station, Dr. David H. Rosmarin, clinical psychologist, author, and Harvard Medical School professor, will lead a refreshingly honest roundtable session that challenges how founders think about fear and pressure. His roundtable, “Thriving with A

Access BMC UART on Supermicro X11SSH

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New 'CitrixBleed 2' NetScaler flaw let hackers hijack sessions

A recent vulnerability in Citrix NetScaler ADC and Gateway is dubbed "CitrixBleed 2," after its similarity to an older exploited flaw that allowed unauthenticated attackers to hijack authentication session cookies from vulnerable devices. Last week, Citrix published a security bulletin warning about flaws tracked as CVE-2025-5777 and CVE-2025-5349 that impact NetScaler ADC and Gateway versions before 14.1-43.56, releases before 13.1-58.32, and also 13.1-37.235-FIPS/NDcPP and 2.1-55.328-FIPS. T

Thanks to Fidelity and our amazing sponsors, TechCrunch All Stage is where startups rise

At TechCrunch All Stage, we’re proud to spotlight our partners — not only for their support, but also for the invaluable expertise they bring to the conversation. Their sessions deliver front-line insights into the startup ecosystem and are must-attend moments for anyone looking to navigate and thrive in today’s dynamic entrepreneurial landscape. We sincerely thank Fidelity, whose support is powering this year’s TC All Stage programming. Their commitment to startup success helps fuel the knowled

Nano-Vllm: lightweight vLLM implementation built from scratch

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Minimal auto-differentiation engine in Rust

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Minimal auto-differentiation engine in Rust (for educational purposes)

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Show HN: Sexprs – Lisp dialect written in Rust

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Show HN: Tiny Hoare logic verifier using SMT

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Guess I'm a Rationalist Now

A week ago I attended LessOnline, a rationalist blogging conference featuring many people I’ve known for years—Scott Alexander, Eliezer Yudkowsky, Zvi Mowshowitz, Sarah Constantin, Carl Feynman—as well as people I’ve known only online and was delighted to meet in person, like Joe Carlsmith and Jacob Falkovich and Daniel Reeves. The conference was at Lighthaven, a bewildering maze of passageways, meeting-rooms, sleeping quarters, gardens, and vines off Telegraph Avenue in Berkeley, which has rece

Apple Camp 2025 brings new iMovie-focused workshops for kids, sign up now

Apple’s free summer workshops for kids are back. Starting today, parents and guardians can register for this year’s edition of Apple Camp, which will run from June 21 through July 31 at Apple Store locations worldwide. See how to register and take home an exclusive T-shirt. The program, aimed at children aged up to 10, is part of Apple’s ongoing Today at Apple initiative. Sessions are designed to get kids hands-on with Apple technology in fun, creative ways, while also giving parents and guardi

Show HN: Trieve CLI – Terminal-based LLM agent loop with search tool for PDFs

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