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This Simple Strategy Could Curb One of Semaglutide’s Worst Side Effects

gizmodo.com Ed Cara 2025-07-19 05:40:47

Semaglutide’s ability to help people lose weight is legendary, but so are the side effects. The active ingredient in medications Wegovy and Ozempic, semaglutide is renowned for causing severe nausea in some people, sometimes to the extent that they stop treatment. But new research published in the journal Diabetes Care suggests there may be a simple way to combat that effect. Led by a team in Israel, the researchers found that giving people more time and flexibility to ramp up to the recommende

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Doctors Are Warning That Ozempic’s Severe Side Effects May Outweigh Its Benefits

futurism.com Unknown 2025-07-29 17:00:41

Image by Roberto Pfeil / picture alliance via Getty / Futurism Rx/Medicines As weight loss jabs like Ozempic and Wegovy become ever more popular, doctors are growing increasingly concerned about their gnarly side effects. As Germany's Deutsche Welle notes, people who take glucagon-like peptide-1 (GLP-1) agonist/receptors, the class of drugs that the popular shots fall under, have reported everything from stomach issues and vision changes to erectile dysfunction and even suicide. Though clinic

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First malaria treatment for babies approved for use

news.ycombinator.com Unknown 2025-07-25 22:16:33

First malaria treatment for babies approved for use 4 days ago Share Save Dominic Hughes Global Health Correspondent Share Save Getty Images Malaria drugs for children do exist, but there are no treatments specifically for babies The first malaria treatment suitable for babies and very young children has been approved for use. It's expected to be rolled out in African countries within weeks. Until now there have been no approved malaria drugs specifically for babies. Instead they have been tr

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New Study Flips Everything We Know About Addiction Upside Down

futurism.com Unknown 2025-07-30 08:05:30

Since the 1970s, countless experts and the US government have sold the public a simple explanation for drug addiction, now clinically called substance abuse disorder: the myth of the gateway drug. The gateway drug — usually cast as weed, alcohol, tobacco, or inhalants — refers to the theory that the earlier a kid starts using drugs, the more likely they are to get into the harder stuff later in life, like heroin or cocaine. Though the idea was pioneered as early as the 1930s, the policy term wa

Topics: brain drug drugs gateway theory

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These Genetically Modified Mice Make Their Own ‘Ozempic’

gizmodo.com Ed Cara 2025-08-04 13:05:53

The popularity of Ozempic and Wegovy as diabetes and weight loss medications has skyrocketed. But how far would people go to avoid one of their major drawbacks—the need for weekly injections? A study out today shows it’s possible to genetically modify mice to make their own Ozempic-like drugs. Scientists in Japan led the research, which involved gene-editing mice’s livers to produce an internal supply of exenatide, a first-generation GLP-1 drug. The edited mice were able to sustain levels of th

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An AI That Promises to “Solve All Diseases” Is About to Test Its First Human Drugs

gizmodo.com Luc Olinga 2025-08-05 18:07:39

Deep inside Alphabet, the parent company of Google, a secretive lab is working on a promise so audacious it sounds like science fiction: to “solve all diseases.” The company, Isomorphic Labs, is now preparing to start its first human clinical trials for cancer drugs designed entirely by artificial intelligence. In a recent interview with Fortune, Colin Murdoch, President of Isomorphic Labs and Chief Business Officer of Google DeepMind, confirmed the company is on the verge of this monumental st

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Colombia seizes first unmanned narco-submarine with Starlink antenna

news.ycombinator.com Unknown 2025-08-10 03:31:21

Photograph released by the Colombian Navy press office showing an unmanned semi-submersible, known as a Low Profile Vessel, between two Colombian Navy vessels, July 2, 2025. The Colombian navy on Wednesday announced its first seizure of an unmanned narco-submarine equipped with a Starlink antenna off its Caribbean coast. The vessel was not carrying drugs, but the Colombian navy and Western security sources based in the region told AFP they believed it was a trial run of an unmanned vessel by a

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RFK Jr.’s plan to put ‘AI’ in everything is a disaster

theverge.com Lauren Leffer 2025-08-14 09:30:00

In a 92-minute interview with Tucker Carlson on Monday, RFK Jr. drilled down on his vision for the US Department of Health and Human Services (HHS). Artificial intelligence — arguably, a uselessly vague umbrella term — came up multiple times. (As did conspiracy theories and disinformation on vaccines and autism, the medical establishment, and covid-19 deaths.) As the head of HHS, Kennedy said his federal department is undergoing an “AI revolution.” He implored viewers to “stop trusting the expe

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Could Ozempic Treat Migraines, Too? Small Study Finds Early Promise for GLP-1s

gizmodo.com Ed Cara 2025-08-20 17:25:30

Got a blinding headache? Some GLP-1 therapy could surprisingly help. A recent clinical trial has found early evidence that these popular drugs, typically used to treat obesity and type 2 diabetes, may also reduce migraine episodes. Researchers in Italy conducted the small pilot trial, which involved dozens of patients living with obesity and chronic migraine headaches. People experienced a significant drop in the number of migraine days each month upon taking liraglutide, the researchers found—

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The Download: how to clean up AI data centers, and weight-loss drugs’ side effects

technologyreview.com Rhiannon Williams 2025-08-23 09:10:00

In a sandy industrial lot outside Reno, Nevada, rows of battery packs that once propelled electric vehicles are now powering a small AI data center. Redwood Materials, one of the US’s largest battery recycling companies, showed off this array of energy storage modules, sitting on cinder blocks and wrapped in waterproof plastic, during a press tour at its headquarters on June 26. The event marked the launch of the company's new business line, Redwood Energy, which will initially repurpose (

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The Next Acetaminophen Tablet You Take Could Be Made From PET

wired.com Fernanda González 2025-08-23 09:53:19

Researchers at the University of Edinburgh have succeeded in transforming certain plastic waste into acetaminophen using the natural properties of the common bacterium Escherichia coli (E. coli). This breakthrough represents a milestone with the potential to drive more sustainable methods of drug production and, at the same time, contribute to the reduction of plastic pollution globally. The study, led by Stephen Wallace, revealed that E. coli cells contain phosphate, an organic compound capabl

Topics: acetaminophen drug plastic production waste

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Spike in Pancreas Problems From Weight-Loss Drugs Prompts Investigation

gizmodo.com Ed Cara 2025-08-25 05:37:46

Ozempic and similar GLP-1 drugs seem to be hurting some people’s pancreas. UK health officials are planning to study the link between GLP-1 use and acute pancreatitis, following an increase in reported cases this year. The Guardian reported Tuesday that the UK’s Medicines and Healthcare Products Regulatory Agency (MHRA) is launching an investigation into pancreatitis associated with the drug class. Hundreds of residents have complained about pancreas problems after taking semaglutide or other r

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Novo Nordisk Abruptly Ends Partnership with Hims, Claiming ‘Sham Compounding’ GLP-1 Drugs

gizmodo.com Ed Cara 2025-08-31 13:04:21

Bad blood is brewing among some major players in the weight loss world. Novo Nordisk, the creator of Ozempic and Wegovy, cut short its partnership with telehealth company Hims & Hers Health Inc. over allegations that the latter is still trying to mass-market cheaper versions of the GLP-1 drugs. Bloomberg News reported the abrupt dissolution of the partnership Monday, just two months after it was struck. Novo claims that Hims is using “deceptive marketing” to widely sell compounded semaglutide t

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Eli Lilly’s Obesity Pill Appears to Work as Well as Injected GLP-1s

wired.com Emily Mullin 2025-09-01 15:01:00

Eli Lilly’s daily anti-obesity pill orforglipron appears to be as good at spurring weight loss and lowering blood sugar in diabetes patients as popular injectable GLP-1 drugs like Ozempic, according to new data from a Phase 3 trial. The results were announced today at the annual meeting of the American Diabetes Association and published in the New England Journal of Medicine. Eli Lilly is the maker of the blockbuster GLP-1 drug tirzepatide, approved as Mounjaro for type 2 diabetes and Zepbound

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The FDA Just Approved a Long-Lasting Injection to Prevent HIV

wired.com Jorge Garay 2025-09-04 02:30:00

The US Food and Drug Administration has just approved lenacapavir, an injectable form of HIV prevention that is almost 100 percent effective and requires only two doses per year. Science magazine described the medicine the most important scientific advance of 2024. In clinical trials, lenacapavir proved to be 99.9 percent effective in preventing HIV infection through sexual transmission in people weighing more than 35 kilograms. The drug, an antiretroviral, works not by stimulating an immune re

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FDA Approves ‘Breakthough’ Drug to Prevent HIV

gizmodo.com Ed Cara 2025-09-06 21:20:18

The Food and Drug Administration has just approved a preventative HIV drug widely regarded as a breakthrough. On Wednesday afternoon, the FDA approved Gilead Sciences’ lenacapavir as a more convenient form of pre-exposure prophylaxis (PrEP). In clinical trials, the drug was shown to be highly effective at preventing HIV infection when taken just twice a year. At the same time, advocates are urging Gilead and U.S. officials to ensure the drug is widely accessible to the public. “PrEP is one of

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Surgery Still Beats Ozempic and Other GLP-1 Drugs in Real-World Weight Loss Study

gizmodo.com Ed Cara 2025-09-09 21:05:43

When it comes to weight loss, surgery still reigns supreme. Research out today shows that people undergoing bariatric surgery tend to lose significantly more weight than people taking the newest, most effective GLP-1 medications for obesity. Scientists at New York University conducted the study, which analyzed real-world data from obesity patients. People who received surgery lost five times more weight over a two year span on average than those who were prescribed a GLP-1 drug, they found. The

Topics: drugs glp people surgery weight

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Threat in Your Medicine Cabinet: The FDA's Gamble on America's Drugs

news.ycombinator.com Debbie Cenziper 2025-09-11 01:10:25

The Food and Drug Administration’s 2022 inspection of the Sun Pharma factory in India warned of contaminations and deficiencies. But the plant received permission from the FDA to continue shipping more than a dozen generic medications to Americans. We are still reporting. If you are a current or former FDA employee or someone in the industry with information about the agency, the safety of generic drugs, or the manufacturers that make them, our team wants to hear from you. Megan Rose can be rea

Topics: agency drugs fda propublica said

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A New Obesity Pill May Burn Fat Without Suppressing Appetite

wired.com Emily Mullin 2025-09-13 08:00:00

An experimental obesity pill that works in a different way from the wildly popular Ozempic may help people lose weight, according to results from a small, preliminary human trial. Ozempic and other GLP-1 drugs reduce food intake by stimulating a feeling of fullness. They act on the brain to promote satiety and on the gut to slow the movement of food through the stomach, helping people feel full longer. As a result, people on the drugs lose weight because they eat less. But a new drug may be ab

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The Download: gambling with humanity’s future, and the FDA under Trump

technologyreview.com Rhiannon Williams 2025-09-13 14:10:00

—Bryan Gardiner This story is from the next print edition of MIT Technology Review, which explores power—who has it, and who wants it. It’s set to go live on Wednesday June 25, so subscribe & save 25% to read it and get a copy of the issue when it lands! Here’s what food and drug regulation might look like under the Trump administration Earlier this week, two new leaders of the US Food and Drug Administration published a list of priorities for the agency. Both Marty Makary and Vinay Prasad

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Here’s what food and drug regulation might look like under the Trump administration

technologyreview.com Jessica Hamzelou 2025-09-14 02:00:00

First, a bit of background. Makary, the current FDA commissioner, is a surgeon and was a professor of health policy at the Johns Hopkins School of Public Health. He initially voiced support for stay-at-home orders during the pandemic but later changed his mind. In February 2021, he incorrectly predicted that the US would “have herd immunity by April.” He has also been very critical of the FDA, writing in 2021 that its then leadership acted like “a crusty librarian” and that drug approvals were “

Topics: care covid drug fda health

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The FDA Is Already Outsourcing Drug and Food Analysis to Error-Plagued AI Chatbot

futurism.com Unknown 2025-09-14 12:08:05

Image by Getty / Futurism In case you haven't had enough about artificial intelligence, the US Food and Drug Administration is now outsourcing its oversight duties to a large language model (LLM.) In an article published in the Journal of the American Medical Association (JAMA), FDA bureaucrats Marty Makary and Vinay Prasad — the latter of whom is a noted critic of COVID mask mandates and vaccine boosters — laid out a five-point list of priorities that the federal agency is hoping to tackle. A

Topics: ai drug elsa fda industry

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Doctors Concerned By Massive Uptick In Teens Taking Ozempic

futurism.com Unknown 2025-09-16 14:15:15

Image by Roberto Pfeil / picture alliance via Getty / Futurism Rx/Medicines Teens are being prescribed Ozempic and similar drugs more than ever before — and some doctors are worried about what the trend could mean. In interviews with Reuters and Raleigh, North Carolina's WRAL, doctors expressed disquiet at recent studies that found that are kids being prescribed the uber-popular jabs at increasing rates. Two recent studies, the first from the from the data firm Truveta and the second from Eve

Topics: doctors drugs glp kids ozempic

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Shares of Hims & Hers tumble 26% after FDA says semaglutide is no longer in shortage

cnbc.com Ashley Capoot 2025-06-02 13:02:43

Shares of Hims & Hers Health closed down around 26% on Friday after the U.S. Food and Drug Administration announced that the shortage of semaglutide injection products has been resolved. Semaglutide is the active ingredient in Novo Nordisk's blockbuster weight loss drug Wegovy and diabetes treatment Ozempic. Those medications are part of a class of drugs called GLP-1s, and demand for the treatments has exploded in recent years. As a result, digital health companies such as Hims & Hers have been

Topics: compounded drugs hims medications semaglutide

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Latest Tech News

This Simple Strategy Could Curb One of Semaglutide’s Worst Side Effects

Doctors Are Warning That Ozempic’s Severe Side Effects May Outweigh Its Benefits

First malaria treatment for babies approved for use

New Study Flips Everything We Know About Addiction Upside Down

These Genetically Modified Mice Make Their Own ‘Ozempic’

An AI That Promises to “Solve All Diseases” Is About to Test Its First Human Drugs

Colombia seizes first unmanned narco-submarine with Starlink antenna

RFK Jr.’s plan to put ‘AI’ in everything is a disaster

Could Ozempic Treat Migraines, Too? Small Study Finds Early Promise for GLP-1s

The Download: how to clean up AI data centers, and weight-loss drugs’ side effects

The Next Acetaminophen Tablet You Take Could Be Made From PET

Spike in Pancreas Problems From Weight-Loss Drugs Prompts Investigation

Novo Nordisk Abruptly Ends Partnership with Hims, Claiming ‘Sham Compounding’ GLP-1 Drugs

Eli Lilly’s Obesity Pill Appears to Work as Well as Injected GLP-1s

The FDA Just Approved a Long-Lasting Injection to Prevent HIV

FDA Approves ‘Breakthough’ Drug to Prevent HIV

Surgery Still Beats Ozempic and Other GLP-1 Drugs in Real-World Weight Loss Study

Threat in Your Medicine Cabinet: The FDA's Gamble on America's Drugs

A New Obesity Pill May Burn Fat Without Suppressing Appetite

The Download: gambling with humanity’s future, and the FDA under Trump

Here’s what food and drug regulation might look like under the Trump administration

The FDA Is Already Outsourcing Drug and Food Analysis to Error-Plagued AI Chatbot

Doctors Concerned By Massive Uptick In Teens Taking Ozempic

Shares of Hims & Hers tumble 26% after FDA says semaglutide is no longer in shortage

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