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Babies made using three people's DNA are born free of mitochondrial disease

Babies made using three people's DNA are born free of hereditary disease 3 days ago Share Save James Gallagher • @JamesTGallagher Health and science correspondent Share Save Watch the moment DNA from a mum and dad is injected into the egg of another woman - the critical step in the creation of a baby made from three people Eight babies have been born in the UK using genetic material from three people to prevent devastating and often fatal conditions, doctors say. The method, pioneered by UK s

The Download: how to run an LLM, and a history of “three-parent babies”

In the early days of large language models, there was a high barrier to entry: it used to be impossible to run anything useful on your own computer without investing in pricey GPUs. But researchers have had so much success in shrinking down and speeding up models that anyone with a laptop, or even a smartphone, can now get in on the action. For people who are concerned about privacy, want to break free from the control of the big LLM companies, or just enjoy tinkering, local models offer a co

A brief history of “three-parent babies”

I can’t go any further without talking about the term we use to describe these children. Journalists, myself included, have called them “three-parent babies” because they are created using DNA from three people. Briefly, the approach typically involves using the DNA from the nuclei of the intended parents’ egg and sperm cells. That’s where most of the DNA in a cell is found. But it also makes use of mitochondrial DNA (mtDNA)—the DNA found in the energy-producing organelles of a cell—from a thir

First malaria treatment for babies approved for use

First malaria treatment for babies approved for use 4 days ago Share Save Dominic Hughes Global Health Correspondent Share Save Getty Images Malaria drugs for children do exist, but there are no treatments specifically for babies The first malaria treatment suitable for babies and very young children has been approved for use. It's expected to be rolled out in African countries within weeks. Until now there have been no approved malaria drugs specifically for babies. Instead they have been tr