Study details enzymes marine bacteria use to break down fucoidan seaweed polysaccharides
Researchers assembled a detailed methods protocol using fucoidans from multiple seaweed species, including Fucus vesiculosus and Laminaria hyperborea, alongside custom LC-MS internal standards and PMP derivatization reagents. They also formulated three seawater-mimicking bacterial growth media to enrich, isolate and cultivate marine microbes capable of degrading these complex sulfated polysaccharides.
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Understanding how ocean bacteria cooperatively break down fucoidan sheds light on marine carbon cycling and could inform biotechnological extraction of fucoidan, a compound valued for pharmaceutical and nutraceutical applications. The careful sourcing of multiple fucoidan variants and standardized media reflects the complexity of studying these polysaccharides, which vary significantly by seaweed species.
- Fucoidans from seven different seaweed species were used to study bacterial degradation pathways.
- Custom isotope-labeled standards enabled precise LC-MS quantification of degradation products.
- Three specialized seawater-like media were developed to enrich, isolate and grow fucoidan-degrading marine bacteria.
Source: nature.com — Sichert, 2026-08-26
Published there as: “Synergistic degradation of fucoidans in the ocean”
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