In the version of this article initially published, in Extended Data Fig. 9e, the H3K4me3 immunoblot was inadvertently duplicated from the H3K27me3 immunoblot during figure assembly. The correct H3K4me3 blot, which derives from the same experiment, is shown in the Supplementary Information below. New exports of all panels from the original source films are provided in the corrected figure; the H3K27me1 panel might appear slightly different from the original owing to a scanning artifact in the original panel (scanner-film contact surface) introduced during digitization of the source films. The original source films are available in a Figshare repository (https://doi.org/10.6084/m9.figshare.33027986). This correction does not affect the results, interpretation or conclusions of the article. Due to the age of the article, the figure cannot be updated directly; this notice serves to correct the article.
Author Correction: Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
Why This Matters
A Nature paper on H3K27 demethylases in acute lymphoblastic leukaemia has been formally corrected after an immunoblot panel was found to have been duplicated during figure assembly. The authors say the correct blot comes from the same experiment and that the conclusions are unaffected, and they have posted the original source films to a public Figshare repository. It's a small but telling example of how post-publication scrutiny of image data is reshaping scientific record-keeping.
Key Takeaways
- An H3K4me3 immunoblot in Extended Data Fig. 9e was inadvertently duplicated from the H3K27me3 panel; the correct blot is now supplied.
- Authors released original source films in a public Figshare repository, reflecting a push toward raw-data transparency.
- The correction does not change the paper's results or conclusions, and the figure itself cannot be updated because of the article's age.
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