Researchers push to develop standardized tests for immune system health
A commentary in Nature argues that current clinical tools—such as white blood cell counts or C-reactive protein tests—only offer a fragmented view of immune function, failing to capture whether a person's immune system is resilient or declining. The authors say advances in immunology, molecular profiling, imaging and AI could enable development of a comprehensive 'immunome' measurement to assess immune health more completely.
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If such measures were developed, they could allow doctors to assess a patient's immune 'biological age' separately from chronological age, potentially flagging risks for neurodegeneration, cancer or mortality before symptoms appear. This suggests a shift toward more personalized, preventive medicine, though translating complex immune network data into a routine clinical test remains a significant scientific and practical challenge.
- Current immune tests like white blood cell counts give only a partial, nonspecific picture of immune health.
- Immune system 'biological age' varies between people of the same chronological age and has been linked to disease risk.
- Advances in molecular profiling, imaging and AI could enable a more holistic 'immunome' health measurement.
Source: nature.com — Aerts, 2026-10-27
Published there as: “Could measuring immune health reshape medical care?”
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