GoKawiil
Tech News
A large-scale genetic study analyzed data from roughly one million people to identify genetic variants associated with the Big Five personality traits—openness, conscientiousness, extraversion, agreeableness, and neuroticism. The research aimed to uncover the biological underpinnings of personality by pinpointing specific genomic regions correlated with these traits.
Researchers analyzed genetic data from more than a million people and identified roughly 1,200 common genetic variants associated with the Big Five personality traits: extroversion, agreeableness, conscientiousness, neuroticism and openness. Published in Nature and led in part by Michel Nivard at the University of Bristol, the work is the largest genetic analysis of personality to date, though each variant explains only a small share of trait variation.
Researchers pooled data from 46 cohorts through the ReGPC consortium to run genome-wide association analyses on personality traits among participants with European-like and African-like ancestry. They applied strict quality controls—filtering low-frequency variants, poor imputation quality, and problematic samples—before analyzing how genetic variants relate to standardized Big Five personality measures.
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