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Multinational study validates Lancet Commission's clinical obesity framework over BMI

Researchers conducted a large multinational analysis testing the Lancet Commission's diagnostic framework for obesity against standard BMI-based classification. The study found that BMI alone both over- and under-identifies obesity, with discordance against combined anthropometric criteria (waist circumference and waist-to-height ratio) ranging from 1.2-3.1% overestimation and 5.2-8.6% underestimation of obesity cases across cohorts.

nature.com · 2026-11-11

Study finds waist-based CAD-obesity metric outperforms BMI in predicting death risk

A Nature-published analysis of more than 800,000 people found that body mass index alone misses many individuals whose excess body fat raises their health risks. Researchers tested a combined measure, CAD-obesity, which pairs BMI with waist circumference and other body-fat indicators, and found it better predicted mortality risk than BMI alone.

nature.com · 2026-11-11