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Brain Aging

2 GoKawiil briefs on this topic

Study finds chimpanzee and gorilla brains don't shrink with age like human brains

Researchers studying brain volume in chimpanzees and gorillas found that, unlike human brains, these great ape brains do not lose significant mass as the animals grow older. The comparison suggests age-related brain shrinkage seen in humans is not a universal feature of ape aging.

PsychAD study maps single-cell gene activity in human brain across full lifespan

Researchers analyzed prefrontal cortex tissue from 284 neurotypical donors aged 0 to 97, drawn from the NIMH HBCC and Mount Sinai NIH Neurobiobank collections, to build a single-cell transcriptomic atlas. Donors were screened using neuropathology criteria such as CERAD and Braak scores to exclude Alzheimer's, Parkinson's, schizophrenia, bipolar disorder and cognitive impairment, and were grouped into developmental, young, middle and late adulthood categories.