GoKawiilStanford study finds human brain forms from two separate progenitor cell types
Researchers led by Kyle Loh at Stanford University found that in mouse and human embryos, the front and back regions of the brain arise from distinct progenitor cells rather than a shared developmental origin. Cells expressing the OTX2 gene generate the forebrain and midbrain, while GBX2-expressing cells produce the hindbrain, a pattern confirmed in both mouse embryos and human cells grown in dishes.