GoKawiil
Tech News
A new bioRxiv preprint analysed DNA methylation patterns in transplanted human hearts and found that, months after surgery, the tissue's biological age markers shifted to resemble the recipient's age rather than the donor's. Researchers observed this effect in both directions: young hearts placed in older bodies appeared to age faster, while older hearts in younger bodies appeared to grow biologically younger.
Renier Brentjens, one of the early researchers behind CAR T cell therapy, is now developing a new generation of engineered 'living drug' treatments. His current work aims to extend the success these therapies have had against blood cancers to solid tumors, which have proven far harder to treat with cell-based approaches.
Researchers report that a young boy's cancer went into remission after receiving an experimental form of CAR T cell therapy. The treatment is part of ongoing efforts to adapt CAR T technology, previously effective mainly against blood cancers, to target solid tumors.