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Cell Biology

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Study finds nuclear pore barrier proteins behave like liquids

Researchers studying the nuclear pore complex, the structure that controls molecular traffic in and out of a cell's nucleus, found that the disordered proteins forming its selective barrier move and behave like a liquid. This fluid-like motion appears to underlie how the pore filters which molecules can pass through it. The finding was published in Nature.

Stanford team transplants human brain organoids into mice, restoring cortex function

Stanford University researchers led by Sergiu Pașca transplanted lab-grown human brain organoids into mice bred to lack most of their cerebral cortex. The transplanted tissue survived and formed functional connections to the animals' brains and spinal cords, according to a study published in Nature. The team describes it as the most extensive integration of human brain cells into an animal achieved to date.