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Cell Culture

3 GoKawiil briefs on this topic

Celleste Bio CEO highlights partnership strategy for cell-cultured cocoa tech

Writing as an Entrepreneur contributor, the CEO of Celleste Bio describes how the company developed cell-culture technology to produce cocoa ingredients, including chocolate-grade cocoa butter already used in milk chocolate. The piece argues that bringing such breakthroughs into established industries requires strategic partnerships alongside proprietary innovation, citing GM CEO Mary Barra's comment that companies now both compete and partner within the same industries.

Study ties tRNA gene dosage to prostate cancer lineage shifts and drug resistance

Researchers at the Fred Hutchinson Cancer Center analyzed metastatic prostate cancer samples and cell line models, including treatment-resistant variants, to study how transfer RNA (tRNA) abundance influences tumor behavior. The work examined patient tumor samples collected via rapid autopsy alongside multiple prostate cancer cell lines adapted to mimic lineage plasticity and resistance to androgen-deprivation therapy.

Study maps 'proximity antigens' on tumor cell surfaces using AI-guided graph learning

Researchers cultured dozens of cancer cell lines alongside normal primary epithelial cells to profile surface proteins near known tumor markers. They applied a graph-learning computational method to identify 'proximity antigens'—proteins located near established cancer targets on the cell membrane—that could serve as new markers for tumor-specific therapies. The work combined wet-lab cell culture across breast, lung, colon, pancreatic, gastric and other cancer types with a novel AI-driven proximity mapping approach.