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Cellular Biology

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DeepMind releases AlphaGenome 2 to predict DNA effects at single-cell level

Google DeepMind has released AlphaGenome 2, a successor to its AlphaGenome genome-prediction model, trained on more than 100 million individual cell profiles across 68 tissues. The model predicts how genetic variants affect specific cell types and states rather than cells broadly, and DeepMind says it identifies nearly twice as many expression-changing variants as its prior best model.