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Cellular Senescence

3 GoKawiil briefs on this topic

Researchers identify protein linked to ageing that bypasses inflammation pathway

Scientists reported discovering a protein that contributes to cellular ageing without triggering the inflammatory response typically associated with senescent cells. The finding separates the ageing-driving function of the protein from the inflammation usually seen in aged tissue, according to the research.

Rubedo Life Sciences reports topical drug cut skin's biological age in small trial

Rubedo Life Sciences, a Mountain View biotech, presented early data at the Aging Research and Drug Discovery meeting showing its experimental topical cream reduced skin biological age by about two years on average in an 11-person trial. The cream targets senescent 'zombie' skin cells in patients with atopic dermatitis, and an independent analysis by Mitra Bio found reduced inflammation markers and a 10 percent rise in elasticity-related collagen after four weeks of use.

Researchers find postmenopausal ovaries remain molecularly active, not dormant

Northwestern University reproductive biologist Francesca Duncan studied ovarian tissue from postmenopausal women aged 50 to 75 and found the protein composition varied significantly across age groups, rather than staying static as assumed. The findings suggest the ovary continues undergoing biological changes for decades after fertility and hormone production have ended.